Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 7/20 | 0.65 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.65 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.65 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.56 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10463487 | 1.00 | TBXAS1 (0.65) | TBXAS1PDE3BPDE3ACRBNTNIK | |
| SCHEMBL10464750 | 0.94 | TBXAS1 (0.63) | TBXAS1PDE3BPDE3ACRBNTNIK | |
| SCHEMBL10464749 | 0.94 | TBXAS1 (0.63) | TBXAS1PDE3BPDE3ACRBNTNIK | |
| SCHEMBL6963342 | 0.90 | TBXAS1 (0.67) | TBXAS1PDE3BPDE3ACRBNTNIK | |
| SCHEMBL6963344 | 0.90 | TBXAS1 (0.67) | TBXAS1PDE3BPDE3ACRBNTNIK | |
| SCHEMBL10464755 | 0.79 | TBXAS1 (1.00) | TBXAS1PDE3BPDE3ACRBNTNIK | |
| SCHEMBL10464756 | 0.79 | TBXAS1 (1.00) | TBXAS1PDE3BPDE3ACRBNTNIK | |
| SCHEMBL10463554 | 0.79 | TBXAS1 (0.57) | TBXAS1PDE3BPDE3ACRBNTNIK | |
| SCHEMBL10461476 | 0.77 | TBXAS1 (0.55) | TBXAS1PDE3BPDE3ACRBNHTR1A | |
| SCHEMBL10836202 | 0.77 | TBXAS1 (0.56) | TBXAS1PDE3BPDE3ACRBNCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921862-A | Carbostyril derivatives as combined thromboxane synthetase and cyclic-amp phosphodiesterase inhibitors | SYNTEX (U.S.A.) INC. (US) | 1990-05-01 | — | — | US | disclosed |
| US-4792561-A | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |