Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 9/20 | 0.63 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.63 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.63 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.54 |
| ▸ | QPCT | Q16769 | 2/20 | 0.42 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10464749 | 1.00 | TBXAS1 (0.63) | TBXAS1PDE3BPDE3ACRBNQPCT | |
| SCHEMBL10463488 | 0.94 | TBXAS1 (0.65) | TBXAS1PDE3BPDE3ACRBNQPCT | |
| SCHEMBL10463487 | 0.94 | TBXAS1 (0.65) | TBXAS1PDE3BPDE3ACRBNQPCT | |
| SCHEMBL6963342 | 0.88 | TBXAS1 (0.67) | TBXAS1PDE3BPDE3ACRBNTNIK | |
| SCHEMBL6963344 | 0.88 | TBXAS1 (0.67) | TBXAS1PDE3BPDE3ACRBNTNIK | |
| SCHEMBL10461476 | 0.80 | TBXAS1 (0.55) | TBXAS1PDE3BPDE3ACRBN | |
| Hydrochloric Acid SCHEMBL10464252 | 0.79 | TBXAS1 (0.54) | TBXAS1PDE3BPDE3ACRBN | |
| SCHEMBL10464344 | 0.79 | HTR1A (0.57) | TBXAS1PDE3BPDE3ACRBN | |
| SCHEMBL10464755 | 0.78 | TBXAS1 (1.00) | TBXAS1PDE3BPDE3ACRBNTNIK | |
| SCHEMBL10464756 | 0.78 | TBXAS1 (1.00) | TBXAS1PDE3BPDE3ACRBNTNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921862-A | Carbostyril derivatives as combined thromboxane synthetase and cyclic-amp phosphodiesterase inhibitors | SYNTEX (U.S.A.) INC. (US) | 1990-05-01 | — | — | US | disclosed |
| US-4792561-A | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |