Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 5/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10464058 | 0.88 | TBXA2R (0.53) | LMNAMEN1KMT2AALDH1A1TBXA2R | |
| SCHEMBL10463281 | 0.88 | AKR1C3 (0.56) | AKR1C3LMNAMEN1MAPTKMT2A | |
| SCHEMBL10460349 | 0.87 | APEX1 (0.46) | AKR1C3F10PRSS1PRSS2PRSS3 | |
| SCHEMBL10463119 | 0.86 | AKR1C3 (0.54) | AKR1C3LMNAMEN1MAPTKMT2A | |
| SCHEMBL10462259 | 0.86 | AKR1C3 (0.56) | AKR1C3F10PRSS1PRSS2PRSS3 | |
| SCHEMBL10463635 | 0.83 | AKR1C3 (0.53) | AKR1C3F10PRSS1PRSS2PRSS3 | |
| SCHEMBL10463612 | 0.82 | RAB9A (0.55) | LMNAMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL10462743 | 0.82 | ALDH1A1 (0.53) | LMNAMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL10461695 | 0.82 | TBXA2R (0.54) | AKR1C3F10PRSS1PRSS2PRSS3 | |
| SCHEMBL10462768 | 0.81 | TBXA2R (0.39) | ADRB1ADRB3MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4948809-A | TREATMENT OF AILMENTS DUE TO THROMBOCYTE AGGREGATION OR KIDNEY DYSFUNCTION | BOEHRINGER MANNHEIM GMBH (DE) | 1990-08-14 | — | — | US | disclosed |