Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.50 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.50 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.50 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.50 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10750201 | 0.77 | KMT2A (0.77) | SMN1; SMN2MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL9790455 | 0.77 | LMNA (0.56) | SMN1; SMN2MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL9790446 | 0.77 | LMNA (0.56) | SMN1; SMN2MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL7285179 | 0.75 | ALDH1A1 (0.73) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL9318255 | 0.75 | MAOB (0.58) | SMN1; SMN2MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL23959500 | 0.75 | EPHX2 (0.58) | SMN1; SMN2MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL9318626 | 0.75 | MAPT (0.49) | MAPTKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL5860896 | 0.75 | ALDH1A1 (0.73) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL9370024 | 0.73 | KMT2A (0.77) | SMN1; SMN2MAPTNLRP3KMT2AMEN1 | |
| SCHEMBL868147 | 0.73 | EPHX2 (0.58) | MAPTKMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4948809-A | TREATMENT OF AILMENTS DUE TO THROMBOCYTE AGGREGATION OR KIDNEY DYSFUNCTION | BOEHRINGER MANNHEIM GMBH (DE) | 1990-08-14 | — | — | US | disclosed |