Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA5A | P35218 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL868147 | 0.80 | EPHX2 (0.58) | EPHX2MEN1KMT2AHDAC8HDAC6 | |
| SCHEMBL6631803 | 0.79 | KCNH2 (0.58) | EPHX2MEN1KMT2AHDAC8HDAC6 | |
| SCHEMBL4528693 | 0.77 | HPGD (0.66) | EPHX2MEN1KMT2AHDAC8HDAC6 | |
| SCHEMBL21620361 | 0.76 | LMNA (0.56) | LMNACA12CA1CA2CA9 | |
| SCHEMBL10463546 | 0.75 | SMN1; SMN2 (0.57) | EPHX2MEN1KMT2AHDAC8HDAC6 | |
| SCHEMBL23959499 | 0.75 | EPHX2 (0.49) | EPHX2MEN1KMT2AGAAHPGD | |
| SCHEMBL11034177 | 0.75 | HDAC8 (0.65) | EPHX2MEN1KMT2AHDAC8HDAC6 | |
| Ammonia Solution, Strong SCHEMBL9177723 | 0.75 | HPGD (0.64) | EPHX2MEN1KMT2AHDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL5023736 | 0.75 | HPGD (0.64) | EPHX2MEN1KMT2AHDAC8HDAC6 | |
| SCHEMBL23933801 | 0.74 | MMP2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021217041-A1 | N-SUBSTITUTED ALPHA-AMINO AND ALPHA-HYDROXY CARBOXAMIDE DERIVATIVES | IMMVENTION THERAPEUTIX (US) | 2021-10-28 | — | — | WO | disclosed |