Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10463165 | 0.87 | HTT (0.50) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL10463835 | 0.87 | ALDH1A1 (0.54) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL10462413 | 0.82 | RAB9A (0.46) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL10460406 | 0.82 | GABRA2 (0.57) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL10462777 | 0.81 | RAB9A (0.45) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL10462776 | 0.80 | CA1 (0.38) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL10463694 | 0.78 | AR (0.57) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL30880273 | 0.77 | GABRA2 (0.47) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL30880271 | 0.77 | GABRA2 (0.47) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL27396018 | 0.77 | GABRA2 (0.47) | ALDH1A1HPGDKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4964896-A | GAMETOCIDES | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| US-4936904-A | Aryl-4-oxonicotinates useful for inducing male sterility in cereal grain plants | MONSANTO TECHNOLOGY LLC | 1990-06-26 | — | — | US | disclosed |
| US-4714492-A | HYBRIDIZATION AGENTS | ROHM AND HAAS COMPANY (US) | 1987-12-22 | — | — | US | disclosed |