SCHEMBL10463565

SCHEMBL10463565

CCOC(=O)C=C1CCOc2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTDSP1 Q9GZU7 4/20 0.43
TDP1 Q9NUW8 1/20 0.43
MAPT P10636 3/20 0.40
LMNA P02545 1/20 0.40
MDM2 Q00987 1/20 0.40
POLB P06746 1/20 0.39
ALDH1A1 P00352 4/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
ESR2 Q92731 1/20 0.38
NOTUM Q6P988 1/20 0.38
KDM4E B2RXH2 3/20 0.37
GAA P10253 1/20 0.37
HPGD P15428 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37
GLA P06280 3/20 0.37
TP53 P04637 1/20 0.36
MAPK1 P28482 1/20 0.36
CASP1 P29466 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29961371 1.00 CTDSP1 (0.43) CTDSP1TDP1MAPTLMNAMDM2
SCHEMBL5480595 1.00 CTDSP1 (0.43) CTDSP1TDP1MAPTLMNAMDM2
SCHEMBL19968929 0.82 RXRA (0.47) MAPTKDM4E
SCHEMBL24867670 0.82 ALDH1A1 (0.39) CTDSP1TDP1MAPTLMNAPOLB
SCHEMBL10407756 0.82 CTDSP1 (0.40) CTDSP1TDP1MAPTLMNAPOLB
SCHEMBL31021614 0.82 ALDH1A1 (0.39) CTDSP1TDP1MAPTLMNAPOLB
SCHEMBL10407623 0.82 USP2 (0.41) CTDSP1TDP1MAPTLMNAPOLB
SCHEMBL10407805 0.81 TDP1 (0.42) CTDSP1TDP1MAPTLMNAPOLB
SCHEMBL1451062 0.80 TRPV1 (0.41) CTDSP1TDP1MAPTALDH1A1NPC1
SCHEMBL12214581 0.80 MAOB (0.59) ALDH1A1NPC1RAB9AHPGDNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2233675-A None JP disclosed
JP-H02233675-A BENZOPYRAN DERIVATIVE, ITS PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME RHONE POULENC SANTE 1990-09-17 JP disclosed