Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 5/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.53 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10463185 | 0.90 | TAS1R3 (0.56) | PTGIRHTTLIPGTAS1R3TAS1R1 | |
| SCHEMBL10358029 | 0.87 | DHODH (0.49) | PTGIRLIPGTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8600077 | 0.80 | PTGIR (0.52) | PTGIRLIPGTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL16977037 | 0.80 | PTGDR2 (0.55) | PTGIRLIPGTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10357606 | 0.80 | PTGIR (0.52) | PTGIRHTTLIPGTBXAS1PTGDR2 | |
| SCHEMBL10357301 | 0.79 | HTT (0.67) | HTTTAS1R3TAS1R1TAS1R2LMNA | |
| SCHEMBL14211188 | 0.77 | PTGDR2 (0.52) | PTGIRLIPGTBXAS1PTGDR2LMNA | |
| SCHEMBL1838407 | 0.77 | PTGIR (0.56) | PTGIRLIPGTBXAS1PTGDR2 | |
| SCHEMBL1838402 | 0.77 | PTGIR (0.56) | PTGIRLIPGTBXAS1PTGDR2 | |
| SCHEMBL8858726 | 0.77 | PTGIR (0.56) | PTGIRTBXAS1PTGDR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921998-A | ANTICOAGULANTS, ANTIISCHEMIC AGENTS, ATHEROSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-01 | — | — | US | disclosed |
| US-4868331-A | ANTICOAGULANTS, ANTIATHEROSCLEROTIC, ANTIISCHEMIC | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-19 | — | — | US | disclosed |