Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.56 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PTGIR | P43119 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10464516 | 0.90 | PTGIR (0.58) | TAS1R3TAS1R1TAS1R2HTTLIPG | |
| SCHEMBL7492500 | 0.79 | KMT2A (0.53) | TAS1R3TAS1R1TAS1R2LMNAKMT2A | |
| SCHEMBL7482096 | 0.78 | PTGIR (0.45) | TAS1R3TAS1R1TAS1R2LMNAMEN1 | |
| SCHEMBL10358029 | 0.78 | DHODH (0.49) | TAS1R3TAS1R1TAS1R2LIPGMEN1 | |
| SCHEMBL10357301 | 0.77 | HTT (0.67) | TAS1R3TAS1R1TAS1R2HTTLMNA | |
| SCHEMBL8411209 | 0.77 | PTGIR (0.56) | PTGIR | |
| SCHEMBL9014591 | 0.76 | PTGIR (0.82) | PTGIR | |
| SCHEMBL8577075 | 0.76 | PTGIR (0.64) | PTGIR | |
| SCHEMBL10463186 | 0.75 | HTT (0.55) | TAS1R3TAS1R1TAS1R2HTTLMNA | |
| SCHEMBL8413684 | 0.75 | PTGIR (0.57) | PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921998-A | ANTICOAGULANTS, ANTIISCHEMIC AGENTS, ATHEROSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-01 | — | — | US | disclosed |
| US-4868331-A | ANTICOAGULANTS, ANTIATHEROSCLEROTIC, ANTIISCHEMIC | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-19 | — | — | US | disclosed |