Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5058209 | 0.93 | HTT (0.49) | ALDH1A1CYP3A4HTTTDP1MAPT | |
| SCHEMBL9464237 | 0.86 | ALDH1A1 (0.57) | ALDH1A1CYP3A4HTTTDP1MAPT | |
| SCHEMBL6375580 | 0.85 | HTT (0.55) | ALDH1A1CYP3A4HTTTDP1MAPT | |
| SCHEMBL1401369 | 0.85 | ALDH1A1 (0.53) | ALDH1A1CYP3A4HTTTDP1MAPT | |
| SCHEMBL3480822 | 0.85 | ALDH1A1 (0.58) | ALDH1A1CYP3A4HTTTDP1MAPT | |
| SCHEMBL4103613 | 0.84 | ALDH1A1 (0.48) | ALDH1A1CYP3A4HTTTDP1MAPT | |
| SCHEMBL8009996 | 0.84 | HTT (0.58) | ALDH1A1CYP3A4HTTTDP1MAPT | |
| SCHEMBL5330357 | 0.81 | HTT (0.50) | ALDH1A1CYP3A4HTTTDP1MAPT | |
| SCHEMBL21070750 | 0.81 | ALDH1A1 (0.49) | ALDH1A1CYP3A4HTTTDP1MAPT | |
| SCHEMBL13557413 | 0.80 | ALDH1A1 (0.51) | ALDH1A1CYP3A4HTTTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4749379-A | HAIR DYES | L'OREAL (FR) | 1988-06-07 | — | — | US | claimed |
| US-4904276-A | Nitroaminophenols, the process for preparation thereof and their use in dyeing keratinous fibres, and new intermediate nitroaminobenzenes and their use in dyeing keratinous fibres | L'OREAL (FR) | 1990-02-27 | — | — | US | disclosed |
| US-4749379-A | HAIR DYES | L'OREAL (FR) | 1988-06-07 | — | — | US | disclosed |