Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GUCY1A1 | Q02108 | 2/20 | 0.37 |
| ▸ | GUCY1B1 | Q02153 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 2/20 | 0.37 |
| ▸ | JAK3 | P52333 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10463266 | 0.95 | CLEC4M (0.43) | CLEC4MGUCY1A1GUCY1B1JAK2JAK3 | |
| SCHEMBL10577664 | 0.75 | CLEC4M (0.43) | CLEC4MTDP1JAK2JAK3KMT2A | |
| SCHEMBL8156087 | 0.68 | TP53 (0.58) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL6765042 | 0.68 | KDM4E (0.54) | L3MBTL1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL22731945 | 0.68 | HSD11B1 (0.53) | POLBAPEX1RECQLCTDSP1TDP1 | |
| SCHEMBL29574308 | 0.68 | HSD11B1 (0.53) | POLBAPEX1RECQLCTDSP1TDP1 | |
| SCHEMBL10464235 | 0.67 | CLEC4M (0.59) | CLEC4MTDP1L3MBTL1KMT2ANPC1 | |
| SCHEMBL1648292 | 0.67 | ALDH1A1 (0.40) | POLBAPEX1RECQLCTDSP1TDP1 | |
| SCHEMBL10464748 | 0.65 | PDE4B (0.39) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL10463764 | 0.64 | TP53 (0.40) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959479-A | PESTICIDES, DRUGS | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) | 1990-09-25 | — | — | US | disclosed |