SCHEMBL10464802

SCHEMBL10464802

O=C(O)c1cccc2nccc(C(=O)O)c12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.48
TDP1 Q9NUW8 1/20 0.48
KDM4A O75164 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
RAB9A P51151 1/20 0.47
EGLN1 Q9GZT9 1/20 0.47
HIF1AN Q9NWT6 1/20 0.47
ALDH1A1 P00352 3/20 0.47
ALOX15 P16050 2/20 0.47
HSD17B10 Q99714 1/20 0.47
CYP3A4 P08684 1/20 0.47
MAPT P10636 1/20 0.47
TSHR P16473 1/20 0.47
BLM P54132 1/20 0.47
AGER Q15109 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
NAPRT Q6XQN6 2/20 0.46
LMNA P02545 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
KDM5A P29375 6/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7031514 0.91 KDM4E (0.44) KDM4ETDP1KDM4AL3MBTL1RAB9A
SCHEMBL15129590 0.85 KDM4E (0.42) KDM4ETDP1KDM4AL3MBTL1RAB9A
SCHEMBL21257069 0.85 KDM5B (0.50) KDM4EKDM4AL3MBTL1RAB9AEGLN1
SCHEMBL21247469 0.85 KDM4E (0.42) KDM4ETDP1KDM4AL3MBTL1RAB9A
SCHEMBL11669054 0.85 TSHR (0.47) KDM4EKDM4AL3MBTL1RAB9AEGLN1
SCHEMBL25261318 0.85 MMP2 (0.46) KDM4ETDP1KDM4AL3MBTL1RAB9A
SCHEMBL28598850 0.82 MAPT (0.52) KDM4ETDP1L3MBTL1RAB9AALDH1A1
SCHEMBL28012268 0.81 DHODH (0.44) KDM4EKDM4AL3MBTL1RAB9AEGLN1
SCHEMBL28012267 0.81 LMNA (0.49) KDM4EKDM4AALDH1A1HSD17B10LMNA
SCHEMBL8545932 0.80 KDM4E (0.50) KDM4ETDP1L3MBTL1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102405039-A Cosmetic or dermatological composition comprising a polymer containing linking groups, and cosmetic treatment method OREAL 2012-04-04 CN claimed
CN-102325518-A Cosmetic or pharmaceutical composition comprising a polycondensate, polycondensate and method of cosmetic treatment OREAL 2012-01-18 CN claimed
US-4968803-A FLUORINE AS OXIDANT ALLIED-SIGNAL INC. (US) 1990-11-06 US disclosed