Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.49 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10466756 | 0.86 | GAA (0.47) | NPSR1NOD1HSPD1PTPN2PTPN1 | |
| SCHEMBL3917085 | 0.79 | CHEK2 (0.67) | NPSR1NOD1NPC1RAB9AKDM4E | |
| SCHEMBL10467765 | 0.75 | ALDH1A1 (0.56) | NPSR1NOD1L3MBTL1NPC1RAB9A | |
| SCHEMBL10466047 | 0.75 | L3MBTL1 (0.67) | NPSR1NOD1L3MBTL1NPC1RAB9A | |
| SCHEMBL8229545 | 0.75 | L3MBTL1 (0.67) | NPSR1NOD1L3MBTL1NPC1RAB9A | |
| SCHEMBL477759 | 0.74 | L3MBTL1 (0.53) | NPSR1NOD1L3MBTL1NPC1RAB9A | |
| SCHEMBL16134479 | 0.74 | CHEK2 (0.55) | NPSR1NOD1L3MBTL1HSPD1PTPN2 | |
| SCHEMBL17702680 | 0.74 | MAPT (0.50) | NPSR1NOD1L3MBTL1HSPD1PTPN2 | |
| SCHEMBL10466744 | 0.73 | RECQL (0.54) | NPSR1NOD1L3MBTL1KDM4EKMT2A | |
| SCHEMBL14642488 | 0.73 | NPSR1 (0.60) | NPSR1NOD1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4943570-A | GASTROINTESTINAL DISORDERS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1990-07-24 | — | — | US | disclosed |
| US-4933338-A | ANTIULCER AGENTS, ANTISECRETORY AGENTS, TREATMENT OF GASTROINTESTINAL DISORDERS; CHEMICAL INTERMEDIATES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1990-06-12 | — | — | US | disclosed |
| EP-0246126-A1 | Benzimidazoles and imidazopyridine sulfone amides, process for their preparation and their use as medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1987-11-19 | — | — | EP | disclosed |