Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30925465 | 0.79 | SLC40A1 (0.62) | ALDH1A1MEN1KMT2AALOX15LMNA | |
| SCHEMBL6738508 | 0.79 | STK33 (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL27214319 | 0.79 | SLC40A1 (0.62) | ALDH1A1MEN1KMT2AALOX15LMNA | |
| SCHEMBL477759 | 0.78 | L3MBTL1 (0.53) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL10466099 | 0.77 | MAPK1 (0.52) | ALDH1A1MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL10466047 | 0.76 | L3MBTL1 (0.67) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL8229545 | 0.76 | L3MBTL1 (0.67) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL5330672 | 0.76 | L3MBTL1 (0.57) | ALDH1A1MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL10464928 | 0.75 | NPSR1 (0.59) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL28577702 | 0.75 | CA2 (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246126-A1 | Benzimidazoles and imidazopyridine sulfone amides, process for their preparation and their use as medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1987-11-19 | — | — | EP | claimed |
| US-4943570-A | GASTROINTESTINAL DISORDERS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1990-07-24 | — | — | US | disclosed |
| US-4933338-A | ANTIULCER AGENTS, ANTISECRETORY AGENTS, TREATMENT OF GASTROINTESTINAL DISORDERS; CHEMICAL INTERMEDIATES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1990-06-12 | — | — | US | disclosed |