Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.35 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15387223 | 0.91 | HRH3 (0.36) | HRH3ALDH1A1POLBMAPTCARM1 | |
| SCHEMBL1515334 | 0.91 | HRH3 (0.36) | HRH3ALDH1A1POLBMAPTCARM1 | |
| SCHEMBL6075113 | 0.89 | CARM1 (0.33) | HRH3ALDH1A1POLBMAPTCARM1 | |
| SCHEMBL1042570 | 0.79 | HTT (0.39) | ALDH1A1MAPTSIGMAR1 | |
| SCHEMBL10465693 | 0.78 | ALDH1A1 (0.43) | ALDH1A1POLB | |
| SCHEMBL10465355 | 0.76 | SIGMAR1 (0.32) | SIGMAR1 | |
| SCHEMBL15387288 | 0.75 | ALDH1A1 (0.35) | ALDH1A1POLBMAPT | |
| SCHEMBL10466010 | 0.74 | ALDH1A1 (0.61) | ALDH1A1POLBMAPTL3MBTL1 | |
| SCHEMBL12677484 | 0.73 | HRH3 (0.44) | HRH3ALDH1A1POLBMAPTCARM1 | |
| SCHEMBL1430804 | 0.73 | ALDH1A1 (0.39) | ALDH1A1SIGMAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4937242-A | CALCIUM ANTAGONISTS | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-06-26 | — | — | US | claimed |
| US-4937242-A | CALCIUM ANTAGONISTS | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-06-26 | — | — | US | disclosed |