Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557368 | 1.00 | KDM4E (0.48) | KDM4EPPARGKEAP1NFE2L2STAT3 | |
| SCHEMBL15669224 | 0.87 | ADAMTS4 (0.42) | ALDH1A1KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL27710803 | 0.86 | STAT3 (0.39) | KDM4EPPARGKEAP1NFE2L2STAT3 | |
| SCHEMBL6461078 | 0.84 | ALDH1A1 (0.44) | STAT3ALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL26377127 | 0.83 | KMT2A (0.43) | KDM4EALDH1A1KMT2AMEN1RECQL | |
| SCHEMBL24103379 | 0.83 | ALDH1A1 (0.40) | KDM4ESTAT3ALDH1A1KMT2AMEN1 | |
| SCHEMBL9306403 | 0.83 | KDM4E (0.44) | KDM4EPPARGKEAP1NFE2L2STAT3 | |
| SCHEMBL19404068 | 0.81 | ALDH1A1 (0.43) | STAT3ALDH1A1KMT2AMEN1RECQL | |
| SCHEMBL8356278 | 0.81 | ALDH1A1 (0.43) | STAT3ALDH1A1KMT2AMEN1RECQL | |
| SCHEMBL18209638 | 0.81 | ALDH1A1 (0.43) | STAT3ALDH1A1KMT2AMEN1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014070092-A1 | FUNCTIONALIZED CELLULOSE NANOCRYSTALS, A METHOD FOR THE PREPARATION THEREOF AND USE OF FUNCTIONALIZED CELLULOSE NANOCRYSTALS IN COMPOSITES AND FOR GRAFTING | SWETREE TECHNOLOGIES AB (SE) | 2014-05-08 | — | — | WO | disclosed |
| US-4968814-A | THIOETHERIFICATION | MERCK & CO., INC. (US) | 1990-11-06 | — | — | US | disclosed |