Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 9/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 8/20 | 0.48 |
| ▸ | TAS1R2 | Q8TE23 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | PYGM | P11217 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10464517 | 0.86 | HTT (0.60) | DHODHTAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL10465487 | 0.80 | TAS1R3 (0.52) | DHODHTAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL10358029 | 0.78 | DHODH (0.49) | DHODHTAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL10465522 | 0.78 | HDAC8 (0.44) | DHODHTAS1R3TAS1R2PYGLPYGM | |
| SCHEMBL10463186 | 0.76 | HTT (0.55) | TAS1R3TAS1R1TAS1R2HTTLMNA | |
| SCHEMBL10464611 | 0.72 | CYP1A2 (0.49) | HTTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL10550188 | 0.72 | KMT2A (0.44) | MEN1KMT2A | |
| SCHEMBL10465060 | 0.71 | CYP1A2 (0.53) | HTTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL10464553 | 0.70 | ACHE (0.39) | TAS1R3TAS1R1TAS1R2HTTLMNA | |
| SCHEMBL9698820 | 0.69 | TAS1R3 (0.58) | DHODHTAS1R3TAS1R1TAS1R2PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921998-A | ANTICOAGULANTS, ANTIISCHEMIC AGENTS, ATHEROSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-01 | — | — | US | disclosed |
| US-4868331-A | ANTICOAGULANTS, ANTIATHEROSCLEROTIC, ANTIISCHEMIC | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-19 | — | — | US | disclosed |