Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 8/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 8/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10464517 | 0.89 | HTT (0.60) | HTTKMT2AMEN1LMNATAS1R3 | |
| SCHEMBL10357301 | 0.78 | HTT (0.67) | HTTKMT2AMEN1LMNATAS1R3 | |
| SCHEMBL10465490 | 0.76 | DHODH (0.48) | HTTKMT2AMEN1LMNATAS1R3 | |
| SCHEMBL10463185 | 0.75 | TAS1R3 (0.56) | HTTKMT2AMEN1LMNATAS1R3 | |
| SCHEMBL10464516 | 0.73 | PTGIR (0.58) | HTTKMT2AMEN1LMNATAS1R3 | |
| SCHEMBL2406255 | 0.72 | HTT (1.00) | HTTKMT2AMEN1LMNATAS1R3 | |
| SCHEMBL1222346 | 0.72 | PTGDR2 (0.41) | TSHR | |
| SCHEMBL2062415 | 0.72 | PTGDR2 (0.41) | TSHR | |
| SCHEMBL2062805 | 0.72 | PTGDR2 (0.41) | TSHR | |
| SCHEMBL5436807 | 0.72 | HTT (1.00) | HTTKMT2AMEN1LMNATAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921998-A | ANTICOAGULANTS, ANTIISCHEMIC AGENTS, ATHEROSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-01 | — | — | US | disclosed |
| US-4868331-A | ANTICOAGULANTS, ANTIATHEROSCLEROTIC, ANTIISCHEMIC | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-19 | — | — | US | disclosed |