Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1047435 | 0.80 | ALDH1A1 (0.38) | CES2CES1USP2LMNAHPGD | |
| SCHEMBL1047437 | 0.80 | ALDH1A1 (0.38) | CES2CES1USP2LMNAHPGD | |
| SCHEMBL6010185 | 0.78 | IDO1 (0.41) | USP2LMNAALOX15ALDH1A1KDM4E | |
| SCHEMBL15648051 | 0.77 | PIK3CD (0.37) | ALDH1A1ADORA2ARBP4KMT2A | |
| SCHEMBL15646669 | 0.75 | MAPT (0.49) | LMNAHTTNPC1ALDH1A1KDM4E | |
| SCHEMBL1045351 | 0.75 | MEN1 (0.46) | HPGDSLMNAHTTALOX15ALDH1A1 | |
| SCHEMBL5216245 | 0.75 | NPC1 (0.50) | HPGDSCES2CES1DAOLMNA | |
| SCHEMBL6182738 | 0.74 | GAA (0.43) | HTTALDH1A1RBP4KMT2ATP53 | |
| SCHEMBL1047472 | 0.73 | CES2 (0.43) | CES2CES1DAOHPGDNPC1 | |
| SCHEMBL5894851 | 0.72 | HTT (0.51) | HPGDSCES2CES1USP2DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8981111-B2 | Fungicide hydroximoyl-heterocycles derivatives | BAYER CROPSCIENCE AG (DE) | 2015-03-17 | — | — | US | disclosed |
| US-20110034445-A1 | FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2011-02-10 | — | — | US | disclosed |
| EP-2271641-A1 | FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES | Bayer CropScience AG (DE) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009130193-A1 | FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2009-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034445-A1 | FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES | HAAO, HPD, CYP51A1 | HPGDS 2507/4885CES2 964/4885CES1 2237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.