Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA5A | P35218 | 3/20 | 0.48 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4006935 | 0.85 | ALDH1A1 (0.51) | ALDH1A1TDP1NPBWR1MAPTMEN1 | |
| SCHEMBL16134487 | 0.85 | L3MBTL1 (0.54) | ALDH1A1TDP1NPBWR1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL6534097 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TDP1NPBWR1MAPTMEN1 | |
| SCHEMBL10465038 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TDP1NPBWR1MAPTMEN1 | |
| SCHEMBL7366348 | 0.80 | KMT2A (0.50) | ALDH1A1TDP1NPBWR1MAPTMEN1 | |
| SCHEMBL10466098 | 0.79 | KDM4E (0.47) | ALDH1A1TDP1NPBWR1MAPTMEN1 | |
| SCHEMBL27912243 | 0.79 | ALDH1A1 (0.45) | ALDH1A1TDP1NPBWR1MAPTMEN1 | |
| SCHEMBL833508 | 0.78 | ALDH1A1 (0.77) | ALDH1A1TDP1NPBWR1MAPTMEN1 | |
| SCHEMBL8559038 | 0.78 | ALDH1A1 (0.53) | ALDH1A1NPBWR1MAPTMEN1KMT2A | |
| SCHEMBL10465972 | 0.76 | MAPKAPK2 (0.47) | ALDH1A1TDP1CA2CA5AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246126-A1 | Benzimidazoles and imidazopyridine sulfone amides, process for their preparation and their use as medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1987-11-19 | — | — | EP | claimed |
| US-4943570-A | GASTROINTESTINAL DISORDERS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1990-07-24 | — | — | US | disclosed |
| US-4933338-A | ANTIULCER AGENTS, ANTISECRETORY AGENTS, TREATMENT OF GASTROINTESTINAL DISORDERS; CHEMICAL INTERMEDIATES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1990-06-12 | — | — | US | disclosed |
| EP-0246126-A1 | Benzimidazoles and imidazopyridine sulfone amides, process for their preparation and their use as medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1987-11-19 | — | — | EP | disclosed |