Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 3/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 3/20 | 0.40 |
| ▸ | MERTK | Q12866 | 3/20 | 0.40 |
| ▸ | GAS6 | Q14393 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10468596 | 0.96 | NR2F2 (0.39) | FLT3TYRO3MERTKGAS6TSHR | |
| SCHEMBL10469377 | 0.94 | NR2F2 (0.38) | FLT3TYRO3MERTKGAS6AXL | |
| SCHEMBL10469415 | 0.89 | NR2F2 (0.41) | FLT3TYRO3MERTKGAS6SYK | |
| SCHEMBL10468781 | 0.89 | KDM4E (0.45) | FLT3L3MBTL1SYK | |
| SCHEMBL10467023 | 0.87 | ROCK2 (0.44) | FLT3TYRO3MERTKGAS6TSHR | |
| SCHEMBL10469376 | 0.86 | ESR1 (0.45) | FLT3TYRO3MERTKGAS6TSHR | |
| SCHEMBL10468245 | 0.85 | ESR1 (0.43) | TSHRTDP1L3MBTL1ESR1 | |
| SCHEMBL10468535 | 0.85 | KDM4E (0.48) | L3MBTL1SYK | |
| SCHEMBL10467450 | 0.84 | TSHR (0.42) | TSHRTDP1L3MBTL1ESR1 | |
| SCHEMBL10468283 | 0.84 | ROCK2 (0.42) | FLT3SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916229-A | Pyridine carboxylic acid derivates | WARNER-LAMBERT COMPANY (US) | 1990-04-10 | — | — | US | disclosed |