Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2F2 | P24468 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.38 |
| ▸ | MERTK | Q12866 | 2/20 | 0.38 |
| ▸ | GAS6 | Q14393 | 2/20 | 0.38 |
| ▸ | ULK1 | O75385 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10467342 | 0.96 | FLT3 (0.40) | SYKFLT3TYRO3MERTKGAS6 | |
| SCHEMBL10469415 | 0.94 | NR2F2 (0.41) | NR2F2NPSR1SYKKDM4EMAPT | |
| SCHEMBL10468535 | 0.89 | KDM4E (0.48) | NR2F2NPSR1SYKKDM4EMAPT | |
| SCHEMBL10469377 | 0.89 | NR2F2 (0.38) | NR2F2NPSR1SYKKDM4EMAPT | |
| SCHEMBL10467083 | 0.87 | NR2F2 (0.42) | NR2F2NPSR1KDM4EMAPTMAPK1 | |
| SCHEMBL10468707 | 0.86 | ESR1 (0.43) | NR2F2NPSR1KDM4EMAPTMAPK1 | |
| SCHEMBL10468781 | 0.85 | KDM4E (0.45) | NR2F2NPSR1SYKKDM4EMAPT | |
| SCHEMBL10467366 | 0.85 | ULK1 (0.43) | SYKFLT3MERTKULK1 | |
| SCHEMBL10466965 | 0.84 | ESR1 (0.46) | NR2F2NPSR1KDM4EMAPTMAPK1 | |
| SCHEMBL10468245 | 0.84 | ESR1 (0.43) | MAPK1LMNATSHRTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916229-A | Pyridine carboxylic acid derivates | WARNER-LAMBERT COMPANY (US) | 1990-04-10 | — | — | US | disclosed |