Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10465937 | 0.95 | PSEN1 (0.46) | CCR1PLA2G2APSEN1PSEN2APH1B | |
| SCHEMBL10467254 | 0.91 | CTSL (0.42) | PLA2G2AGAAMAPTPKMKDM4E | |
| SCHEMBL10467764 | 0.84 | CNR2 (0.45) | KDM4ELMNATRPM8CTSLCTSS | |
| SCHEMBL10468124 | 0.78 | CCR1 (0.43) | CCR1MAPTLMNAALDH1A1TRPM8 | |
| SCHEMBL10467337 | 0.78 | TRPM8 (0.47) | LMNAALDH1A1TRPM8CTSLCTSS | |
| SCHEMBL10776104 | 0.78 | TRPM8 (0.47) | LMNAALDH1A1TRPM8CTSLCTSS | |
| SCHEMBL10465913 | 0.74 | MEN1 (0.42) | MAPTLMNAALDH1A1TRPM8OPRK1 | |
| SCHEMBL10466593 | 0.73 | PSEN1 (0.54) | PLA2G2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10467546 | 0.71 | TRPM8 (0.45) | GAAKDM4ELMNAALDH1A1TRPM8 | |
| SCHEMBL10469072 | 0.69 | TRPM8 (0.47) | KDM4ELMNAALDH1A1TRPM8CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4940709-A | PLATELET ACTIVATING FACTOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-07-10 | — | — | US | disclosed |
| US-4806538-A | ANTICOAGULANT, HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-21 | — | — | US | disclosed |