Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10468470 | 0.89 | MAPT (0.39) | KMT2APOLBALDH1A1HPGDMAPT | |
| SCHEMBL10468020 | 0.80 | NOS3 (0.39) | ALDH1A1RAB9ANPC1KDM4EKIF11 | |
| SCHEMBL14975958 | 0.78 | KMT2A (0.49) | KMT2APOLBALDH1A1HPGDMAPT | |
| SCHEMBL14975956 | 0.78 | KMT2A (0.49) | KMT2APOLBALDH1A1HPGDMAPT | |
| SCHEMBL10341773 | 0.71 | POLB (0.57) | KMT2APOLBALDH1A1HPGDMAPT | |
| SCHEMBL11793571 | 0.71 | NOS3 (0.46) | KMT2APOLBALDH1A1HPGDMAPT | |
| SCHEMBL10469338 | 0.69 | NOS3 (0.35) | KMT2AMAPTRAB9ALMNASMN1; SMN2 | |
| SCHEMBL8636414 | 0.68 | POLB (0.51) | KMT2APOLBALDH1A1HPGDMAPT | |
| SCHEMBL14999393 | 0.68 | POLB (0.51) | KMT2APOLBALDH1A1HPGDMAPT | |
| SCHEMBL10932532 | 0.67 | KMT2A (0.50) | KMT2APOLBALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4965284-A | IMMUNOMODULATORS | AMERICAN CYANAMID COMPANY (US) | 1990-10-23 | — | — | US | claimed |