Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.35 |
| ▸ | NOS1 | P29475 | 3/20 | 0.35 |
| ▸ | NOS2 | P35228 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | IDE | P14735 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10513467 | 0.92 | BCKDK (0.34) | NOS3NOS1NOS2 | |
| SCHEMBL4870613 | 0.87 | NOS3 (0.35) | NOS3NOS1NOS2MEN1MAPT | |
| SCHEMBL4865586 | 0.69 | MAOA (0.34) | KMT2A | |
| SCHEMBL10341922 | 0.67 | ATM (0.41) | NOS3NOS1NOS2MEN1MAPT | |
| SCHEMBL10468020 | 0.66 | NOS3 (0.39) | NOS3NOS1NOS2RAB9A | |
| SCHEMBL10341772 | 0.62 | KMT2A (0.40) | NOS3NOS1MEN1KMT2AL3MBTL1 | |
| SCHEMBL10533408 | 0.59 | ALDH1A1 (0.41) | NOS3NOS1NOS2MAPTSMN1; SMN2 | |
| SCHEMBL13437908 | 0.59 | RAB9A (0.48) | NOS3NOS1NOS2MAPTRAB9A | |
| SCHEMBL10531339 | 0.59 | MAPK1 (0.48) | MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL10514018 | 0.58 | IAPP (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4965284-A | IMMUNOMODULATORS | AMERICAN CYANAMID COMPANY (US) | 1990-10-23 | — | — | US | claimed |
| EP-0342433-A2 | Substituted dibenzothiaphenes | AMERICAN CYANAMID COMPANY (US) | 1989-11-23 | — | — | EP | claimed |