Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1045128 | 0.89 | GAA (0.42) | KDM4ETSHRGAACCR1CYP1A2 | |
| SCHEMBL1046910 | 0.87 | GAA (0.40) | KDM4EALDH1A1TSHRGAACCR1 | |
| SCHEMBL27975032 | 0.86 | KDM4E (0.34) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL1046922 | 0.86 | GAA (0.40) | ALDH1A1HPGDTSHRGAACCR1 | |
| SCHEMBL1047598 | 0.85 | GAA (0.39) | KDM4ETSHRGAACCR1CYP1A2 | |
| SCHEMBL27975034 | 0.84 | L3MBTL1 (0.34) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL1774525 | 0.81 | GAA (0.43) | KDM4ETSHRGAACCR1CYP1A2 | |
| SCHEMBL13523714 | 0.81 | GAA (0.50) | KDM4EALDH1A1HPGDL3MBTL1TSHR | |
| SCHEMBL1046923 | 0.81 | GAA (0.40) | KDM4ETSHRGAACCR1CYP1A2 | |
| SCHEMBL1270565 | 0.80 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130090477-A1 | Thiazolylpiperidine Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2013-04-11 | — | — | US | disclosed |
| US-20130090476-A1 | Thiazolylpiperidine Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2013-04-11 | — | — | US | disclosed |
| US-20110046178-A1 | Thiazolylpiperidine Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2011-02-24 | — | — | US | disclosed |
| EP-2272846-A1 | Thiazolylpiperidine derivatives as fungicide | Bayer CropScience AG (DE) | 2011-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090476-A1 | Thiazolylpiperidine Derivatives as Fungicides | NAT1, GRHPR, PTPRG | KDM4E 2882/4885ALDH1A1 693/4885HPGD 1956/4885 |
| US-20130090477-A1 | Thiazolylpiperidine Derivatives as Fungicides | NAT1, GRHPR, PTPRG | KDM4E 2882/4885ALDH1A1 693/4885HPGD 1956/4885 |
| US-20110046178-A1 | Thiazolylpiperidine Derivatives as Fungicides | NAT1, GRHPR, PTPRG | KDM4E 2882/4885ALDH1A1 693/4885HPGD 1956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.