Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1044102 | 0.89 | GAA (0.40) | GAACCR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27975267 | 0.87 | TRPV1 (0.33) | GAATRPV1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1047599 | 0.87 | GAA (0.38) | GAACCR1TRPV1CYP1A2CYP3A4 | |
| SCHEMBL1046909 | 0.85 | KDM4E (0.41) | GAACCR1TRPV1CYP1A2CYP3A4 | |
| SCHEMBL1046922 | 0.84 | GAA (0.40) | GAACCR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27975270 | 0.84 | TRPV1 (0.30) | TRPV1 | |
| SCHEMBL1046923 | 0.80 | GAA (0.40) | GAACCR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1046643 | 0.80 | GAA (0.47) | GAACCR1SPRKDM4EPOLB | |
| SCHEMBL1047445 | 0.80 | GAA (0.39) | GAACCR1SPRKDM4EPOLB | |
| SCHEMBL1046910 | 0.80 | GAA (0.40) | GAACCR1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130090477-A1 | Thiazolylpiperidine Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2013-04-11 | — | — | US | disclosed |
| US-20130090476-A1 | Thiazolylpiperidine Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2013-04-11 | — | — | US | disclosed |
| US-20110046178-A1 | Thiazolylpiperidine Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2011-02-24 | — | — | US | disclosed |
| EP-2272846-A1 | Thiazolylpiperidine derivatives as fungicide | Bayer CropScience AG (DE) | 2011-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090476-A1 | Thiazolylpiperidine Derivatives as Fungicides | NAT1, GRHPR, PTPRG | GAA 70/4885CCR1 2185/4885TRPV1 3281/4885 |
| US-20130090477-A1 | Thiazolylpiperidine Derivatives as Fungicides | NAT1, GRHPR, PTPRG | GAA 70/4885CCR1 2185/4885TRPV1 3281/4885 |
| US-20110046178-A1 | Thiazolylpiperidine Derivatives as Fungicides | NAT1, GRHPR, PTPRG | GAA 70/4885CCR1 2185/4885TRPV1 3281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.