Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10467888 | 0.84 | KIF11 (0.43) | NCOA1NCOA3GSTP1ARPTGS2 | |
| SCHEMBL8129827 | 0.83 | NCOA1 (0.47) | SLC6A2SLC6A4SLC6A3FFAR4NCOA1 | |
| SCHEMBL27269465 | 0.82 | PTGS2 (0.43) | SLC6A2SLC6A4SLC6A3FFAR4NCOA1 | |
| SCHEMBL6098760 | 0.82 | KIF11 (0.43) | SLC6A4NCOA1NCOA3AR | |
| SCHEMBL6098538 | 0.81 | NCOA1 (0.47) | SLC6A2SLC6A4SLC6A3FFAR4NCOA1 | |
| SCHEMBL27272353 | 0.81 | LTA4H (0.50) | NCOA1NCOA3GSTP1PTGS2LTA4H | |
| SCHEMBL27269469 | 0.81 | PTGS2 (0.41) | SLC6A2SLC6A4SLC6A3FFAR4NCOA1 | |
| SCHEMBL875186 | 0.81 | FFAR4 (0.39) | FFAR4ARFFAR1 | |
| SCHEMBL10469325 | 0.80 | GAA (0.43) | SLC6A2SLC6A4SLC6A3FFAR4NCOA1 | |
| SCHEMBL4463855 | 0.79 | DRD1 (0.35) | FFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4975451-A | Insecticidal cyclopropyl di(aryl) 2-butenes | FMC CORPORATION (US) | 1990-12-04 | — | — | US | disclosed |