Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364462 | 0.77 | ADRA2A (0.43) | OPRM1HTR2BSIGMAR1ADRB2HTR1A | |
| SCHEMBL7570951 | 0.75 | KDM1A (0.50) | SIGMAR1ADRA2ASLC6A2SLC6A3OTUD7B | |
| SCHEMBL8635505 | 0.75 | ALDH1A1 (0.41) | ADRA2AHTR5AOTUD7BKDM4EALDH1A1 | |
| SCHEMBL1570433 | 0.74 | APP (0.35) | HTR5AOTUD7BKDM4EMEN1ALDH1A1 | |
| SCHEMBL6568601 | 0.73 | KDM1A (0.41) | SIGMAR1KDM4EALDH1A1KMT2APOLA1 | |
| SCHEMBL1571868 | 0.69 | PTGDR2 (0.42) | PTGDR2 | |
| SCHEMBL10469011 | 0.67 | POLA1 (0.40) | ALDH1A1KMT2APOLA1PTGDR2 | |
| SCHEMBL19278346 | 0.66 | GAA (0.38) | KDM4EMEN1NPC1ALDH1A1GAA | |
| SCHEMBL20762065 | 0.65 | EGFR (0.33) | ADRA2AADRA2BKDM4EALDH1A1GAA | |
| SCHEMBL16836035 | 0.65 | ADRA2A (0.40) | ADRA2AHTR5AOTUD7BKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4957914-A | ANTIDEPRESSANTS, ANXIOLYTICS, HYPOTENSIVE AGENTS | SYNTEX (U.S.A.) INC. (US) | 1990-09-18 | — | — | US | disclosed |