Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.37 |
| ▸ | HTR5A | P47898 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570951 | 0.92 | KDM1A (0.50) | ADRA2AKDM1AKDM4EJAK2ALDH1A1 | |
| SCHEMBL8635505 | 0.92 | ALDH1A1 (0.41) | ADRA2AKDM4EJAK2ALDH1A1HPGD | |
| SCHEMBL23891554 | 0.84 | ADRA2A (0.38) | ADRA2AKDM4EJAK2ALDH1A1HPGD | |
| SCHEMBL6568601 | 0.84 | KDM1A (0.41) | KDM1AKDM4EJAK2ALDH1A1HPGD | |
| SCHEMBL1530577 | 0.83 | BACE1 (0.35) | KDM1AKDM4EJAK2ALDH1A1HPGD | |
| SCHEMBL7980930 | 0.83 | KDM1A (0.37) | KDM1A | |
| SCHEMBL1570433 | 0.80 | APP (0.35) | KDM4EJAK2ALDH1A1HPGDDRD2 | |
| SCHEMBL7973198 | 0.80 | KDM1A (0.36) | KDM1AALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL10469737 | 0.77 | OPRM1 (0.33) | ADRA2AKDM4EALDH1A1OTUD7BHTR5A | |
| SCHEMBL17605796 | 0.76 | ALDH1A1 (0.41) | ADRA2AKDM4EALDH1A1OTUD7BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0275104-B1 | Process for preparing 2,3-dihydro-1H-imidazolylalkoxyindene derivatives and pharmaceutically acceptable salts, and intermediate therefor | FERRER INT (ES) | 1994-01-19 | — | — | EP | disclosed |
| EP-0275104-A2 | Process for preparing 2,3-dihydro-1H-imidazolylalkoxyindene derivatives and pharmaceutically acceptable salts, and intermediate therefor | FERRER INTERNACIONAL, S.A. (ES) | 1988-07-20 | — | — | EP | disclosed |