Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9751984 | 0.82 | HSP90AA1 (0.74) | HSP90AA1IDO1ALDH1A1ALOX12TAAR1 | |
| SCHEMBL3296809 | 0.80 | IDO1 (0.61) | IDO1ALDH1A1MAPTLMNACNR2 | |
| SCHEMBL4007444 | 0.78 | KDM4E (0.64) | CALM1IDO1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL10470450 | 0.77 | HSPA5 (0.64) | HSP90AA1IDO1ALDH1A1CYP3A4MAPT | |
| SCHEMBL10987745 | 0.77 | HSPA5 (0.64) | IDO1ALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL10470441 | 0.76 | ALDH1A1 (0.62) | CALM1IDO1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL22800045 | 0.74 | IDO1 (0.52) | IDO1ALDH1A1MAPTCNR2TAAR1 | |
| SCHEMBL10470235 | 0.74 | CALM1 (0.54) | CALM1IDO1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL8149029 | 0.73 | CNR2 (0.47) | IDO1CNR2TAAR1CHRM2CHRM1 | |
| SCHEMBL24403685 | 0.73 | HSP90AA1 (0.49) | HSP90AA1IDO1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4979978-A | Herbicidal 12H-dibenzo[d,g][1,3]dioxocin-6-carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1990-12-25 | — | — | US | disclosed |