Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 5/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LIG1 | P18858 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 5/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12562851 | 0.82 | HSD17B1 (0.61) | HSD17B1HSD17B2KDM4ENPC1RAB9A | |
| SCHEMBL9933404 | 0.80 | HSD17B1 (0.59) | HSD17B1HSD17B2KDM4ENPC1RAB9A | |
| SCHEMBL12562792 | 0.80 | HSD17B1 (0.59) | HSD17B1HSD17B2KDM4ENPC1RAB9A | |
| SCHEMBL12562798 | 0.80 | HSD17B1 (0.59) | HSD17B1HSD17B2KDM4ENPC1RAB9A | |
| SCHEMBL12562788 | 0.80 | HSD17B1 (0.59) | HSD17B1HSD17B2KDM4ENPC1RAB9A | |
| SCHEMBL12581415 | 0.79 | HSD17B1 (0.63) | HSD17B1HSD17B2KDM4ENPC1RAB9A | |
| SCHEMBL16200702 | 0.79 | PLAU (0.48) | ALDH1A1HPGDPKMLIG1PLAU | |
| SCHEMBL10630495 | 0.79 | ALDH1A1 (0.39) | HSD17B1HSD17B2KDM4ENPC1RAB9A | |
| SCHEMBL12562796 | 0.77 | HSD17B1 (0.61) | HSD17B1HSD17B2KDM4ENPC1RAB9A | |
| SCHEMBL19364753 | 0.74 | RAB9A (0.39) | KDM4ENPC1RAB9AHPGDPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4939165-A | Miticides | FMC CORPORATION | 1990-07-03 | — | — | US | disclosed |
| EP-0219525-A1 | PHOTOACTIVE BITHIENYL PESTICIDES | FMC Corporation (US) | 1987-04-29 | — | — | EP | disclosed |
| WO-1986005949-A1 | PHOTOACTIVE BITHIENYL PESTICIDES | FMC CORPORATION (US) | 1986-10-23 | — | — | WO | disclosed |