Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PPIA | P62937 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14228268 | 0.79 | MGMT (0.48) | MAPTCYP19A1LMNAMEN1KMT2A | |
| Glycine SCHEMBL10470638 | 0.79 | PTPN1 (0.41) | MAPTCYP19A1LMNAMEN1KMT2A | |
| SCHEMBL12253970 | 0.78 | PTPN1 (0.47) | MAPTCYP19A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL10473218 | 0.78 | MEN1 (0.40) | MAPTCYP19A1LMNAMEN1KMT2A | |
| SCHEMBL25359757 | 0.75 | CYP19A1 (0.58) | MAPTCYP19A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL12253971 | 0.74 | ALDH1A1 (0.46) | MAPTKMT2AL3MBTL1PTPN1RAB9A | |
| SCHEMBL29291232 | 0.73 | ALDH1A1 (0.47) | MAPTCYP19A1LMNAMEN1KMT2A | |
| SCHEMBL14199920 | 0.72 | GLRA1 (0.46) | MAPTCYP19A1LMNAMEN1KMT2A | |
| SCHEMBL14199913 | 0.72 | MEN1 (0.53) | MAPTLMNAMEN1KMT2APKM | |
| SCHEMBL14450789 | 0.71 | HPGD (0.47) | MAPTMEN1KMT2AL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4942227-A | ANTITUMOR AGENTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1990-07-17 | — | — | US | disclosed |