Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MGMT | P16455 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL10470638 | 0.91 | PTPN1 (0.41) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL12253970 | 0.83 | PTPN1 (0.47) | MEN1KMT2AMAPTSMN1; SMN2PTPN1 | |
| SCHEMBL12253971 | 0.79 | ALDH1A1 (0.46) | KMT2AMAPTALDH1A1POLBPTPN1 | |
| SCHEMBL10470640 | 0.78 | LTA4H (0.48) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL14228268 | 0.77 | MGMT (0.48) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL14199914 | 0.75 | HPGD (0.47) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL14450789 | 0.75 | HPGD (0.47) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL28537310 | 0.75 | ALDH1A1 (0.46) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL14199913 | 0.74 | MEN1 (0.53) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL14199912 | 0.74 | HPGD (0.46) | MEN1KMT2AMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4942227-A | ANTITUMOR AGENTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1990-07-17 | — | — | US | disclosed |