⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3027384 | 1.00 | — | — | |
| SCHEMBL4716785 | 0.80 | — | — | |
| SCHEMBL5194477 | 0.80 | — | — | |
| SCHEMBL7674469 | 0.76 | — | — | |
| SCHEMBL8030867 | 0.76 | — | — | |
| SCHEMBL7678678 | 0.74 | — | — | |
| SCHEMBL9726224 | 0.74 | ALDH1A1 (0.42) | — | |
| SCHEMBL9726226 | 0.74 | ALDH1A1 (0.42) | — | |
| SCHEMBL4543673 | 0.74 | ALDH1A1 (0.42) | — | |
| SCHEMBL7348833 | 0.72 | EPHX1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011032159-A1 | METHODS TO PREVENT A HAIR-RELATED SIDE EFFECT OF TREATMENT WITH A CHEMOTHERAPEUTIC AGENT | META COMESTICS, LLC (US) | 2011-03-17 | — | — | WO | claimed |
| US-20110002866-A1 | METHODS TO PREVENT A HAIR-RELATED SIDE EFFECT OF TREATMENT WITH A CHEMOTHERAPEUTIC AGENT | LUBIT BEVERLY W | 2011-01-06 | — | — | US | claimed |
| US-5962686-A | FUNGICIDES | HOFFMANN-LA ROCHE INC. (US) | 1999-10-05 | — | — | US | claimed |
| US-5900486-A | FUNGICIDES | HOFFMANN-LA ROCHE INC. (US) | 1999-05-04 | — | — | US | claimed |
| US-5807984-A | CONTROLLING DISEASES; PENTAPEPTIDES | BASF AKTIENEGESELLSCHAFT (DE) | 1998-09-15 | — | — | US | claimed |
| WO-2011032159-A1 | METHODS TO PREVENT A HAIR-RELATED SIDE EFFECT OF TREATMENT WITH A CHEMOTHERAPEUTIC AGENT | META COMESTICS, LLC (US) | 2011-03-17 | — | — | WO | disclosed |
| US-20110002866-A1 | METHODS TO PREVENT A HAIR-RELATED SIDE EFFECT OF TREATMENT WITH A CHEMOTHERAPEUTIC AGENT | LUBIT BEVERLY W | 2011-01-06 | — | — | US | disclosed |
| WO-2010039535-A1 | COMPOSITIONS AND METHODS TO TREAT EPITHELIAL-RELATED CONDITIONS | META COSMETICS, LLC (US) | 2010-04-08 | — | — | WO | disclosed |
| US-20100074857-A1 | COMPOSITIONS AND METHODS TO TREAT EPITHELIAL-RELATED CONDITIONS | LIPKIN PAMELA | 2010-03-25 | — | — | US | disclosed |
| US-7459561-B2 | N-substituted carbamoyloxyalkyl-azolium derivatives | BASILEA PHARMACEUTICA AG (CH) | 2008-12-02 | — | — | US | disclosed |
| US-7189858-B2 | N-phenyl substituted carbamoyloxyalkyl-azolium derivatives | BASILEA PHARMACEUTICA AG (CH) | 2007-03-13 | — | — | US | disclosed |
| US-20070027322-A1 | N-substituted carbamoyloxyalkyl-azolium derivatives | BASILEA PHARMACEUTICA INTERNATIONAL LTD. (CH) | 2007-02-01 | — | — | US | disclosed |
| US-20050038075-A1 | Intermediates for N-substituted carbamoyloxyalkyl-azolium derivatives | BASILEA PHARMACEUTICA INTERNATIONAL LTD. (CH) | 2005-02-17 | — | — | US | disclosed |
| US-6812238-B1 | WATER SOLUBLE FUNGICIDES FOR SYSTEMIC MYCOSES; ORAL AND PARENTERAL ADMINISTRATION | BASILEA PHARMACEUTICA AG (CH) | 2004-11-02 | — | — | US | disclosed |
| EP-1280795-A2 | N-SUBSTITUTED CARBAMOYLOXYALKYL-AZOLIUM DERIVATIVES | Basilea Pharmaceutica AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| WO-2001032652-A2 | N-SUBSTITUTED CARBAMOYLOXYALKYL-AZOLIUM DERIVATIVES | BASILEA PHARMACEUTICA AG (CH) | 2001-05-10 | — | — | WO | disclosed |
| US-5962686-A | FUNGICIDES | HOFFMANN-LA ROCHE INC. (US) | 1999-10-05 | — | — | US | disclosed |
| US-5900486-A | FUNGICIDES | HOFFMANN-LA ROCHE INC. (US) | 1999-05-04 | — | — | US | disclosed |
| EP-0829478-A2 | N-Benzylimidazolium and N-benzyltriazolium derivatives, their preparation and their use as antifungal and antimycotic agents | F. HOFFMANN-LA ROCHE AG (CH) | 1998-03-18 | — | — | EP | disclosed |
| EP-0126344-A2 | Tripeptide esters of therapeutic agents | ABBOTT LABORATORIES (US) | 1984-11-28 | — | — | EP | disclosed |