Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21099292 | 0.80 | GRM4 (0.53) | GRM4PTGS2GAAKDM4EKMT2A | |
| SCHEMBL10472164 | 0.80 | LMNA (0.57) | GAAKDM4EKMT2ATDP1NOTUM | |
| SCHEMBL7717408 | 0.79 | MEN1 (0.51) | GAAKDM4EKMT2ANOTUMSMN1; SMN2 | |
| SCHEMBL7476038 | 0.75 | NOTUM (0.58) | GAAKDM4EKMT2ATDP1NOTUM | |
| SCHEMBL8812148 | 0.74 | HPGD (0.41) | GAAKDM4EKMT2ANOTUMRAB9A | |
| SCHEMBL25215843 | 0.74 | LMNA (0.60) | GRM4PTGS2KDM4EKMT2ATLR7 | |
| SCHEMBL1290437 | 0.74 | HPGD (0.44) | KDM4EKMT2ATDP1NOTUM | |
| SCHEMBL5624766 | 0.70 | L3MBTL1 (0.40) | KDM4ENOTUMSMN1; SMN2L3MBTL1PKM | |
| SCHEMBL7471354 | 0.69 | CYP2C19 (0.57) | GAANAMPTKMT2ANOTUMRAB9A | |
| SCHEMBL30761577 | 0.69 | CNR1 (0.58) | PTGS2GAAKDM4EKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4963686-A | INTERMEDIATES FOR INOTROPIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1990-10-16 | — | — | US | disclosed |