SCHEMBL1047418

SCHEMBL1047418

O=C(O)CCCCCCn1ccnc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 18/20 1.00
EGLN3 Q9H6Z9 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5538850 1.00 TBXAS1 (1.00) TBXAS1EGLN3
SCHEMBL5539944 1.00 TBXAS1 (1.00) TBXAS1EGLN3
SCHEMBL3137867 1.00 TBXAS1 (1.00) TBXAS1EGLN3
SCHEMBL5535247 1.00 TBXAS1 (1.00) TBXAS1EGLN3
SCHEMBL5533203 1.00 TBXAS1 (1.00) TBXAS1EGLN3
SCHEMBL11272759 1.00 TBXAS1 (1.00) TBXAS1EGLN3
SCHEMBL11269252 1.00 TBXAS1 (1.00) TBXAS1EGLN3
SCHEMBL5531525 1.00 TBXAS1 (1.00) TBXAS1EGLN3
SCHEMBL5541351 1.00 TBXAS1 (1.00) TBXAS1EGLN3
SCHEMBL5536323 1.00 TBXAS1 (1.00) TBXAS1EGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116718657-A Preparation method of glucose biological sensing membrane and glucose biological sensor 深圳木芯科技有限公司 2023-09-08 CN claimed
EP-0351755-B1 COMBINATION OF A CALCIUM CHANNEL BLOCKER AND THROMBOXANE A2 RECEPTOR ANTAGONIST OR SYNTHETASE INHIBITOR AND METHOD FOR TREATING ISCHEMIA EMPLOYING SUCH COMBINATION E.R. SQUIBB & SONS, INC. (US) 1992-09-30 EP claimed
EP-0351755-A1 Combination of a calcium channel blocker and thromboxane A2 receptor antagonist or synthetase inhibitor and method for treating ischemia employing such combination E.R. SQUIBB & SONS, INC. (US) 1990-01-24 EP claimed
CN-116718657-A Preparation method of glucose biological sensing membrane and glucose biological sensor 深圳木芯科技有限公司 2023-09-08 CN disclosed
CN-114787200-A Method for forming inclusion complex using hydrophilic beta-cyclodextrin derivatives and compositions thereof 塔卡美国公司 2022-07-22 CN disclosed
US-20200347153-A1 METHODS FOR FORMING INCLUSION COMPLEXES WITH HYDROPHILIC BETA-CYCLODEXTRIN DERIVATIVES AND COMPOSITIONS THEREOF TAKA USA, INC. (US) 2020-11-05 US disclosed
US-20110002866-A1 METHODS TO PREVENT A HAIR-RELATED SIDE EFFECT OF TREATMENT WITH A CHEMOTHERAPEUTIC AGENT LUBIT BEVERLY W 2011-01-06 US disclosed
CN-100543032-C Streptogramin derivatives, preparation method and compositions containing them AVETIS PHARMA S A (FR) 2009-09-23 CN disclosed
CN-1961878-A Streptogramin derivatives, their preparation and compositions containing them AVENTIS PHARMA SA (FR) 2007-05-16 CN disclosed
US-20070044831-A1 Electrolyte composition and dye-sensitized solar cell NATIONAL UNIVERSITY CORPORATION KYUSHU INSTITUTE OF TECHNOLOGY (JP) 2007-03-01 US disclosed
CN-1358194-A Streptogramin derivatives, preparation method and compositions containing them AVETIS PHARMA S A (FR) 2002-07-10 CN disclosed
EP-0297621-B1 Cyclic amino-thioacetal amides, a process for the preparation thereof and pharmaceutical compositions containing them BOEHRINGER MANNHEIM ITALIA (IT) 1994-09-21 EP disclosed
US-H1139-H Reduced myocardial infarction size and angina pain; prevention of reocclusion with no adverse side effects E. R. SQUIBB & SONS, INC. (US) 1993-02-02 US disclosed
EP-0351755-B1 COMBINATION OF A CALCIUM CHANNEL BLOCKER AND THROMBOXANE A2 RECEPTOR ANTAGONIST OR SYNTHETASE INHIBITOR AND METHOD FOR TREATING ISCHEMIA EMPLOYING SUCH COMBINATION E.R. SQUIBB & SONS, INC. (US) 1992-09-30 EP disclosed
US-4988701-A Cyclic amino-thioacetal amides, a process for the preparation thereof and pharmaceutical compositions BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) 1991-01-29 US disclosed
EP-0351755-A1 Combination of a calcium channel blocker and thromboxane A2 receptor antagonist or synthetase inhibitor and method for treating ischemia employing such combination E.R. SQUIBB & SONS, INC. (US) 1990-01-24 EP disclosed
EP-0297621-A2 Cyclic amino-thioacetal amides, a process for the preparation thereof and pharmaceutical compositions containing them BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1989-01-04 EP disclosed
US-4355170-A ANTIINFLAMMATORY, HYPERTENSIVE, ANTIASTHMATIC AGENTS, A THROMBOXANE SYNTHETASE INHIBITORS ONO PHARMACEUTICAL CO., LTD. (JP) 1982-10-19 US disclosed
US-4320134-A HYPOTENSIVE, ANTIASTHMATIC AND ANTIINFLAMMATORY AGENTS ONO PHARMACEUTICAL CO., LTD. (JP) 1982-03-16 US disclosed
US-4256757-A ANTIINFLAMMATORY AND HYPOTENSIVE AGENTS; THROMBOSIS; ASTHMA; NERVOUS SYSTEM DISORDERS ONO PHARMACEUTICAL CO., LTD. 1981-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110002866-A1 METHODS TO PREVENT A HAIR-RELATED SIDE EFFECT OF TREATMENT WITH A CHEMOTHERAPEUTIC AGENT PGF, PTGS1, PTGS2 TBXAS1 3617/4885EGLN3 202/4885
US-20200347153-A1 METHODS FOR FORMING INCLUSION COMPLEXES WITH HYDROPHILIC BETA-CYCLODEXTRIN DERIVATIVES AND COMPOSITIONS THEREOF DSC1, PDCD2L, GANC TBXAS1 4363/4885EGLN3 4530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.