Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10474273 | 1.00 | KDM4E (0.68) | KDM4ECA1CA2NFKB1CA4 | |
| SCHEMBL2855381 | 0.83 | MAPT (0.53) | KDM4ENFKB1MAPTLMNAMAOB | |
| SCHEMBL1536573 | 0.81 | KDM4E (1.00) | KDM4ECA1CA2NFKB1CA4 | |
| SCHEMBL162076 | 0.81 | KDM4E (0.77) | KDM4ECA1CA2NFKB1CA4 | |
| SCHEMBL1536574 | 0.81 | KDM4E (1.00) | KDM4ECA1CA2NFKB1CA4 | |
| SCHEMBL162075 | 0.81 | KDM4E (0.77) | KDM4ECA1CA2NFKB1CA4 | |
| SCHEMBL474092 | 0.80 | ALDH1A1 (0.46) | KDM4ECA1CA2MAPTMAOB | |
| SCHEMBL474093 | 0.80 | ALDH1A1 (0.46) | KDM4ECA1CA2MAPTMAOB | |
| SCHEMBL7485678 | 0.78 | KDM4E (0.88) | KDM4ECA1CA2NFKB1CA4 | |
| SCHEMBL8488847 | 0.77 | KDM4E (0.91) | KDM4ECA1CA2NFKB1CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4973696-A | Stereoselective process for preparing optically active alpha, beta-disubstituted carbonyl compounds | ZAMBON S.P.A. (IT) | 1990-11-27 | — | — | US | disclosed |
| EP-0236566-A2 | Stereoselective process for preparing optically active alpha, beta-disubstituted carbonyl compounds | ZAMBON S.p.A. (IT) | 1987-09-16 | — | — | EP | disclosed |