Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL474093 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTMEN1TP53 | |
| SCHEMBL31318868 | 0.81 | RAB9A (0.42) | ALDH1A1KDM4EMAPTCYP1A2CYP2C19 | |
| SCHEMBL10474273 | 0.80 | KDM4E (0.68) | KDM4EMAPTCA1CA2MAOB | |
| SCHEMBL10474271 | 0.80 | KDM4E (0.68) | KDM4EMAPTCA1CA2MAOB | |
| SCHEMBL10438847 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTMEN1TP53 | |
| SCHEMBL69522 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTMEN1TP53 | |
| SCHEMBL11061667 | 0.77 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTMEN1TP53 | |
| SCHEMBL2855381 | 0.74 | MAPT (0.53) | ALDH1A1KDM4EMAPTMEN1CYP1A2 | |
| SCHEMBL31111018 | 0.74 | ALDH1A1 (0.38) | ALDH1A1KDM4EMAPTMEN1TP53 | |
| SCHEMBL2933196 | 0.73 | IAPP (0.67) | ALDH1A1KDM4EMAPTMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1348696-B1 | Use of optically active clausenamides for the preparation of pharmaceutical compositions, pharmaceutical compositions containing the same | INST MATERIA MEDICA CAMS (CN) | 2012-02-01 | — | — | EP | disclosed |
| US-6787564-B2 | FOR TREATING HYPOXIA PROTECTIVE, NOOTROPIC AND NEURODEGENERATIVE DISEASES (CERBRAL ISCHEMIA, ALZHEIMER'S DISEASE, AND VASCULAR DEMENTIA) | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2004-09-07 | — | — | US | disclosed |
| US-20030207935-A1 | Novel optically active clausenamides, process of the preparation thereof, pharmaceutical composition containing the same and their medical use | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES | 2003-11-06 | — | — | US | disclosed |
| EP-1348696-A1 | Optically active clausenamides, process of the preparation thereof, pharmaceutical composition containing the same and their medical use | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2003-10-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207935-A1 | Novel optically active clausenamides, process of the preparation thereof, pharmaceutical composition containing the same and their medical use | HIF1AN, HIF1A, CLN6 | ALDH1A1 1464/4885KDM4E 3778/4885MAPT 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.