Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 6/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.51 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.51 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.51 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.51 |
| ▸ | TYR | P14679 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10474271 | 0.83 | KDM4E (0.68) | MAPTLMNAMAOBKDM4ENFKB1 | |
| SCHEMBL10474273 | 0.83 | KDM4E (0.68) | MAPTLMNAMAOBKDM4ENFKB1 | |
| SCHEMBL9006476 | 0.80 | MAPT (0.69) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL30363244 | 0.77 | MAPT (0.55) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL29569445 | 0.75 | MAPT (0.62) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL474093 | 0.74 | ALDH1A1 (0.46) | MAPTMAOBTYRKDM4EKMT2A | |
| SCHEMBL474092 | 0.74 | ALDH1A1 (0.46) | MAPTMAOBTYRKDM4EKMT2A | |
| SCHEMBL10893208 | 0.74 | MAPT (0.75) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL29420130 | 0.74 | MAPT (0.75) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL31549898 | 0.74 | MAPT (0.60) | MAPTRAB9ANPC1LMNABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115368268-B | Method for efficiently preparing azo compound and application thereof | 大连理工大学 | 2023-11-17 | — | — | CN | claimed |
| CN-115368268-A | Method for efficiently preparing azo compound and application thereof | 大连理工大学 | 2022-11-22 | — | — | CN | claimed |
| CN-104926628-B | A kind of synthetic method of benzil analog derivative | 浙江工业大学 | 2016-08-24 | — | — | CN | claimed |
| CN-104262295-B | The synthetic method of a kind of epoxy chalcone and derivative thereof | JIANG University OF TECHNOLOGY (CN) | 2016-05-11 | — | — | CN | claimed |
| CN-104926628-A | Method for synthesizing benzil derivative | UNIV ZHEJIANG TECHNOLOGY | 2015-09-23 | — | — | CN | claimed |
| CN-1990482-B | Flavanonol compounds and their production method and use | ZHEJIANG HISUN PHARM CO LTD | 2010-12-08 | — | — | CN | claimed |
| CN-1990482-A | Flavanonol compounds and their production method and use | ZHEJIANG HISUN NATURELITE PHAR (CN) | 2007-07-04 | — | — | CN | claimed |
| CN-1990485-A | Silybin flavonolignan and their production method and use | ZHEJIANG HISUN NATURELITE PHAR (CN) | 2007-07-04 | — | — | CN | claimed |
| CN-115368268-B | Method for efficiently preparing azo compound and application thereof | 大连理工大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-115368268-A | Method for efficiently preparing azo compound and application thereof | 大连理工大学 | 2022-11-22 | — | — | CN | disclosed |
| CN-104926628-B | A kind of synthetic method of benzil analog derivative | 浙江工业大学 | 2016-08-24 | — | — | CN | disclosed |
| CN-104926628-B | A kind of synthetic method of benzil analog derivative | 浙江工业大学 | 2016-08-24 | — | — | CN | disclosed |
| CN-104262295-B | The synthetic method of a kind of epoxy chalcone and derivative thereof | JIANG University OF TECHNOLOGY (CN) | 2016-05-11 | — | — | CN | disclosed |
| CN-104262295-B | The synthetic method of a kind of epoxy chalcone and derivative thereof | JIANG University OF TECHNOLOGY (CN) | 2016-05-11 | — | — | CN | disclosed |
| US-20090092624-A1 | Antiinfective Flavononol Compounds and Methods of Use Thereof | HERBALSCIENCE GROUP, LLC | 2009-04-09 | — | — | US | disclosed |
| WO-2009026179-A2 | ANTIINFECTIVE PROANTHOCYANIDIN COMPOUNDS AND METHODS OF USE THEREOF | HERBALSCIENCE GROUP LLC (US) | 2009-02-26 | — | — | WO | disclosed |
| WO-2009026166-A2 | ANTIINFECTIVE FLAVONOL COMPOUNDS AND METHODS OF USE THEREOF | HERBALSCIENCE GROUP LLC (US) | 2009-02-26 | — | — | WO | disclosed |
| WO-2009026176-A2 | ANTIINFECTIVE FLAVONONOL COMPOUNDS AND METHODS OF USE THEREOF | HERBALSCIENCE GROUP LLC (US) | 2009-02-26 | — | — | WO | disclosed |
| US-7371578-B2 | Method of evaluating the catalytic activity of a rare earth alkoxide | KABUSHIKIKAISHA KOJUNDOKAGAKU KENKYUSHO (JP) | 2008-05-13 | — | — | US | disclosed |
| US-20030228698-A1 | Method of evaluating the catalytic activity of a rare earth alkoxide | KABUSHIKIKAISHA KOJUNDOKAGAKU KENKYUSHO (JP) | 2003-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090092624-A1 | Antiinfective Flavononol Compounds and Methods of Use Thereof | MPO, VIP, FABP2 | MAPT 3504/4885RAB9A 2628/4885NPC1 258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.