SCHEMBL1047428

SCHEMBL1047428

CCCCOc1ccc(CI)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.53
CYP1A2 P05177 3/20 0.42
CYP2D6 P10635 3/20 0.42
CYP2C9 P11712 2/20 0.42
CYP2C19 P33261 2/20 0.42
CYP19A1 P11511 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TSHR P16473 3/20 0.42
HTT P42858 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
LMNA P02545 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
KCNA3 P22001 1/20 0.41
KDM4E B2RXH2 1/20 0.41
PDE4A P27815 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1044357 0.84 LTA4H (0.53) LTA4HCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL1046791 0.84 LTA4H (0.53) LTA4HCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL7533420 0.82 LTA4H (0.64) LTA4HTSHRHTTSMN1; SMN2LMNA
SCHEMBL5169443 0.81 NR5A1 (0.58) LTA4HTSHR
SCHEMBL21379240 0.80 NR5A1 (0.61) LTA4HTSHRSMN1; SMN2LMNA
SCHEMBL2238977 0.79 LTA4H (0.55) LTA4HCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL1042646 0.77 ALDH1A1 (0.54) LTA4HCYP1A2CYP2D6L3MBTL1TSHR
SCHEMBL15086546 0.77 LMNA (0.53) LTA4HCYP1A2CYP2C19L3MBTL1TSHR
SCHEMBL13428412 0.75 CYP3A4 (0.55) LTA4HKCNA3HDAC10HDAC6
SCHEMBL1331014 0.75 LTA4H (0.87) LTA4HCYP1A2CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530617-B2 Silicon-containing particle, process for producing the same, organic-polymer composition, ceramic, and process for producing the same DOW CORNING TORAY COMPANY, LTD. (JP) 2013-09-10 US disclosed
EP-2461397-A1 ELECTRODE ACTIVE MATERIAL, ELECTRODE, AND ELECTRICITY STORAGE DEVICE Dow Corning Toray Co., Ltd. (JP) 2012-06-06 EP disclosed
US-20110045963-A1 Silicon-Containing Particles, Method For Manufacturing Thereof, Oil Composition, Ceramic Material, And Method For Manufacturing Thereof DOW CORNING TORAY COMPANY, LTD. (JP) 2011-02-24 US disclosed
EP-2271702-A2 SILICON-CONTAINING PARTICLES, METHOD FOR MANUFACTURING THEREOF, OIL COMPOSITION, CERAMIC MATERIAL, AND METHOD FOR MANUFACTURING THEREOF Dow Corning Toray Co., Ltd. (JP) 2011-01-12 EP disclosed
EP-2241586-A1 SILICON-CONTAINING PARTICLE, PROCESS FOR PRODUCING THE SAME, ORGANIC-POLYMER COMPOSITION, CERAMIC, AND PROCESS FOR PRODUCING THE SAME Dow Corning Toray Co., Ltd. (JP) 2010-10-20 EP disclosed
WO-2009133765-A2 SILICON-CONTAINING PARTICLES, METHOD FOR MANUFACTURING THEREOF, OIL COMPOSITION, CERAMIC MATERIAL, AND METHOD FOR MANUFACTURING THEREOF DOW CORNING TORAY CO., LTD. (JP) 2009-11-05 WO disclosed