Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1269920 | 0.92 | ALDH1A1 (0.45) | ALDH1A1LMNATSHRSMN1; SMN2TDP1 | |
| SCHEMBL1047445 | 0.87 | GAA (0.39) | ALDH1A1TSHRSMN1; SMN2GAAKDM4E | |
| SCHEMBL1046420 | 0.87 | GAA (0.40) | ALDH1A1LMNATSHRSMN1; SMN2HPGD | |
| SCHEMBL27974967 | 0.86 | ALDH1A1 (0.47) | ALDH1A1LMNATSHRSMN1; SMN2TDP1 | |
| SCHEMBL27974955 | 0.84 | ALDH1A1 (0.43) | ALDH1A1LMNATSHRSMN1; SMN2TDP1 | |
| SCHEMBL1045128 | 0.82 | GAA (0.42) | TSHRMAPTGAAKDM4EPOLB | |
| SCHEMBL1269936 | 0.81 | ALDH1A1 (0.58) | ALDH1A1LMNATSHRSMN1; SMN2TDP1 | |
| SCHEMBL1775261 | 0.81 | POLB (0.46) | ALDH1A1LMNATSHRHPGDKMT2A | |
| SCHEMBL13523714 | 0.80 | GAA (0.50) | ALDH1A1LMNATSHRHPGDGAA | |
| SCHEMBL12897363 | 0.79 | GPR119 (0.53) | ALDH1A1LMNATSHRSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130090476-A1 | Thiazolylpiperidine Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2013-04-11 | — | — | US | disclosed |
| US-20130090477-A1 | Thiazolylpiperidine Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2013-04-11 | — | — | US | disclosed |
| EP-2445907-A1 | THIAZOLYLPIPERIDINE DERIVATES AS FUNGICIDES | Bayer Cropscience AG (DE) | 2012-05-02 | — | — | EP | disclosed |
| US-20110046178-A1 | Thiazolylpiperidine Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2011-02-24 | — | — | US | disclosed |
| EP-2272846-A1 | Thiazolylpiperidine derivatives as fungicide | Bayer CropScience AG (DE) | 2011-01-12 | — | — | EP | disclosed |
| WO-2010149275-A1 | THIAZOLYLPIPERIDINE DERIVATES AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090476-A1 | Thiazolylpiperidine Derivatives as Fungicides | NAT1, GRHPR, PTPRG | ALDH1A1 693/4885LMNA 2081/4885TSHR 243/4885 |
| US-20130090477-A1 | Thiazolylpiperidine Derivatives as Fungicides | NAT1, GRHPR, PTPRG | ALDH1A1 693/4885LMNA 2081/4885TSHR 243/4885 |
| US-20110046178-A1 | Thiazolylpiperidine Derivatives as Fungicides | NAT1, GRHPR, PTPRG | ALDH1A1 693/4885LMNA 2081/4885TSHR 243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.