Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10284707 | 0.87 | TAAR1 (0.54) | TAAR1SLC6A2LMNACYP2D6TP53 | |
| SCHEMBL13679208 | 0.87 | SLC6A2 (0.48) | TAAR1SLC6A2LMNACYP2D6TP53 | |
| SCHEMBL11147321 | 0.83 | SLC6A2 (0.45) | TAAR1SLC6A2LMNACYP2D6TP53 | |
| SCHEMBL24713157 | 0.81 | SLC6A2 (0.52) | TAAR1SLC6A2LMNACYP2D6TP53 | |
| SCHEMBL27410576 | 0.81 | SLC6A2 (0.52) | TAAR1SLC6A2LMNACYP2D6TP53 | |
| SCHEMBL18469309 | 0.80 | SLC6A2 (0.42) | TAAR1SLC6A2LMNACYP2D6TP53 | |
| SCHEMBL20608245 | 0.80 | ALDH1A1 (0.48) | TAAR1SLC6A2LMNACYP2D6TRPA1 | |
| SCHEMBL20608244 | 0.80 | ALDH1A1 (0.48) | TAAR1SLC6A2LMNACYP2D6TRPA1 | |
| SCHEMBL4352224 | 0.80 | SLC6A2 (0.56) | TAAR1SLC6A2LMNACYP2D6TP53 | |
| SCHEMBL5164402 | 0.78 | SLC6A2 (0.54) | TAAR1SLC6A2LMNACYP2D6TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9820963-B2 | Composition containing lignan compound as active ingredient for preventing or treating cancer | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2017-11-21 | — | — | US | disclosed |
| US-20160228402-A1 | COMPOSITION CONTAINING LIGNAN COMPOUND AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2016-08-11 | — | — | US | disclosed |
| EP-2277393-A1 | Sucralose-containing composition | SAN-EI GEN F.F.I., INC. (JP) | 2011-01-26 | — | — | EP | disclosed |
| US-7662419-B2 | Sucralose-containing composition and edible products containing the composition | SAN-EI GEN F.F.I., INC (JP) | 2010-02-16 | — | — | US | disclosed |
| CN-101188948-A | Lignan-containing compositions | ARCHER DANIELS MIDLAND CO (US) | 2008-05-28 | — | — | CN | disclosed |
| US-7029717-B1 | Sucralose-containing composition and edible products containing the composition | SAN-EI GEN F.F.I., INC. (JP) | 2006-04-18 | — | — | US | disclosed |
| US-20050142271-A1 | Sucralose-containing composition and edible products containing the composition | SAN-EI GEN F.F.I., INC | 2005-06-30 | — | — | US | disclosed |
| EP-1526833-A1 | USE OF LIGNANS FOR PREVENING OR TREATING THE SINGS OF AGEING OF THE SKIN | L'OREAL (FR) | 2005-05-04 | — | — | EP | disclosed |
| CN-1146553-C | HYDROXYMATAIRESINOL for preventing cancer | ��Ī��˹ҩƷ��˾ | 2004-04-21 | — | — | CN | disclosed |
| WO-2004010965-A1 | USE OF LIGNANS FOR PREVENING OR TREATING THE SINGS OF AGEING OF THE SKIN | L'OREAL (FR) | 2004-02-05 | — | — | WO | disclosed |
| CN-1345315-A | HYDROXYMATAIRESINOL for preventing cancer | HORMOS NUTRACEUTICAL OY LTD (FI) | 2002-04-17 | — | — | CN | disclosed |
| EP-1177728-A1 | SUCRALOSE-CONTAINING COMPOSITION AND EATABLE PRODUCT COMPRISING THE SAME | SAN-EI GEN F.F.I., INC. (JP) | 2002-02-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160228402-A1 | COMPOSITION CONTAINING LIGNAN COMPOUND AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER | LCT, BRCA1, ALOX5 | TAAR1 4134/4885SLC6A2 4664/4885LMNA 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.