Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.64 |
| ▸ | ACHE | P22303 | 3/20 | 0.52 |
| ▸ | DHFR | P00374 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2911039 | 0.92 | TAAR1 (0.62) | TAAR1ACHEDHFRMAOBTSHR | |
| SCHEMBL4569094 | 0.90 | TAAR1 (0.51) | TAAR1DHFRCA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL3020991 | 0.90 | TAAR1 (0.60) | TAAR1ACHEDHFRMAOBTSHR | |
| SCHEMBL7991368 | 0.90 | TAAR1 (0.60) | TAAR1DHFRTSHRCYP2D6 | |
| SCHEMBL17402422 | 0.89 | TSHR (0.62) | TAAR1DHFRTSHRCYP2D6 | |
| SCHEMBL9583212 | 0.89 | TSHR (0.62) | TAAR1DHFRTSHRCYP2D6 | |
| Hydrochloric Acid SCHEMBL28001157 | 0.87 | TSHR (0.60) | TAAR1DHFRKMT2ATSHRCYP2D6 | |
| SCHEMBL146849 | 0.86 | TAAR1 (0.68) | TAAR1ACHEDHFRMAOBCA1 | |
| SCHEMBL30820845 | 0.86 | TAAR1 (0.68) | TAAR1ACHEDHFRMAOBCA1 | |
| SCHEMBL2538910 | 0.86 | DHFR (0.54) | TAAR1DHFRMAOBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11690390-B2 | Taste modifying product | FIRMENICH SA (CH) | 2023-07-04 | — | — | US | disclosed |
| EP-2912954-B1 | Taste modifying product and use thereof | FIRMENICH & CIE (CH) | 2023-03-22 | — | — | EP | disclosed |
| US-20220264923-A1 | Taste Modifying Product | FIRMENICH SA (CH) | 2022-08-25 | — | — | US | disclosed |
| US-20220177417-A1 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED 2-[2-(PHENYL) ETHYLAMINO]ALKANEAMIDE DERIVATIVES | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2022-06-09 | — | — | US | disclosed |
| CN-112168824-B | Application of aporphine compound | 苏州大学 | 2022-05-24 | — | — | CN | disclosed |
| US-11291231-B2 | Taste modifying product | FIRMENICH SA (CH) | 2022-04-05 | — | — | US | disclosed |
| US-11224243-B2 | Taste-modifying combinations | FIRMENICH SA (CH) | 2022-01-18 | — | — | US | disclosed |
| EP-2934182-B1 | TASTE-MODIFYING COMBINATIONS | FIRMENICH & CIE (CH) | 2021-07-28 | — | — | EP | disclosed |
| CN-104883904-B | Taste modifying compositions | 弗门尼舍有限公司 | 2021-04-06 | — | — | CN | disclosed |
| CN-112168824-A | Application of aporphine compound | 苏州大学 | 2021-01-05 | — | — | CN | disclosed |
| EP-0789577-A1 | SYNTHESIS OF N-SUBSTITUTED OLIGOMERS | CHIRON CORPORATION (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1996040202-A1 | SYNTHESIS OF N-SUBSTITUTED OLIGOMERS | CHIRON CORPORATION (US) | 1996-12-19 | — | — | WO | disclosed |
| US-5536853-A | Opiate receptor ligands | CHIRON CORPORATION (US) | 1996-07-16 | — | — | US | disclosed |
| US-5480871-A | TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | CHIRON CORPORATION (US) | 1996-01-02 | — | — | US | disclosed |
| WO-1995027729-A1 | OPIATE RECEPTOR LIGANDS | CHIRON CORPORATION (US) | 1995-10-19 | — | — | WO | disclosed |
| US-5447916-A | Hypotensive agents | CHIRON CORPORATION (US) | 1995-09-05 | — | — | US | disclosed |
| WO-1995004072-A1 | PEPTOID ALPHA-1 ADRENERGIC RECEPTOR LIGANDS | CHIRON CORPORATION (US) | 1995-02-09 | — | — | WO | disclosed |
| EP-0170524-B1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-07-15 | — | — | EP | disclosed |
| US-4968698-A | FUNGICIDES, ANTIPROTOZOA AGENTS | BURROUGHS WELLCOME CO. (US) | 1990-11-06 | — | — | US | disclosed |
| EP-0170524-A2 | Nitrogen containing heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-02-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11291231-B2 | Taste modifying product | TAS2R5, TAS2R1, TAS2R45 | TAAR1 1901/4885ACHE 3425/4885DHFR 2943/4885 |
| US-11690390-B2 | Taste modifying product | TAS2R5, TAS2R1, TAS2R45 | TAAR1 1869/4885ACHE 3373/4885DHFR 2834/4885 |
| US-20220264923-A1 | Taste Modifying Product | TAS2R5, TAS2R1, TAS2R45 | TAAR1 1869/4885ACHE 3373/4885DHFR 2834/4885 |
| US-20220177417-A1 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED 2-[2-(PHENYL) ETHYLAMINO]ALKANEAMIDE DERIVATIVES | PKD2, BCKDK, ALK | TAAR1 3187/4885ACHE 2135/4885DHFR 1540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.