Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12489603 | 0.87 | ALDH1A1 (0.83) | ALDH1A1MAPK1NPC1RAB9ATP53 | |
| SCHEMBL1042409 | 0.82 | NPC1 (0.47) | ALDH1A1MAPK1NPC1RAB9ATP53 | |
| SCHEMBL8036362 | 0.82 | LMNA (0.50) | ALDH1A1MAPK1NPC1RAB9ATP53 | |
| SCHEMBL18462293 | 0.80 | NPC1 (0.46) | ALDH1A1MAPK1NPC1RAB9ATP53 | |
| SCHEMBL673353 | 0.80 | MAPK1 (0.71) | ALDH1A1MAPK1NPC1RAB9ATP53 | |
| SCHEMBL3778039 | 0.80 | ALDH1A1 (0.90) | ALDH1A1MAPK1NPC1RAB9ATP53 | |
| SCHEMBL30121160 | 0.80 | ALDH1A1 (0.90) | ALDH1A1MAPK1NPC1RAB9ATP53 | |
| Ethane SCHEMBL27598501 | 0.80 | ALDH1A1 (0.90) | ALDH1A1MAPK1NPC1RAB9ATP53 | |
| SCHEMBL115115 | 0.79 | ALDH1A1 (1.00) | ALDH1A1MAPK1NPC1RAB9ATP53 | |
| SCHEMBL30451936 | 0.79 | ALDH1A1 (1.00) | ALDH1A1MAPK1NPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108679-A | Preparation method of N- (triphenylmethyl) -5- (4' -methylbiphenyl-2-yl) tetrazole | 南京法恩化学有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-108017557-B | Cyanidation method for preparing nitrile compound | 中国科学院兰州化学物理研究所苏州研究院 | 2020-11-24 | — | — | CN | claimed |
| CN-102304056-B | 3-methyl-4-aryl-3-alkenyl-butyryl-pentafluoroaniline derivatives and preparation method thereof | UNIV ZHEJIANG | 2013-12-11 | — | — | CN | claimed |
| CN-102304056-A | 3-methyl-4-aryl-3-alkenyl-butyryl-pentafluoroaniline derivatives and preparation method thereof | UNIV ZHEJIANG | 2012-01-04 | — | — | CN | claimed |
| CN-118852159-A | Heterogeneous palladium-catalyzed selective bell wood coupling reaction and application thereof in Wilmofini intermediate synthesis | 哈尔滨工业大学(深圳)(哈尔滨工业大学深圳科技创新研究院) | 2024-10-29 | — | — | CN | disclosed |
| CN-118271283-A | Synthesis method of 9, 10-dithio (hetero) phenanthrene | 中南大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-118108679-A | Preparation method of N- (triphenylmethyl) -5- (4' -methylbiphenyl-2-yl) tetrazole | 南京法恩化学有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-118108679-A | Preparation method of N- (triphenylmethyl) -5- (4' -methylbiphenyl-2-yl) tetrazole | 南京法恩化学有限公司 | 2024-05-31 | — | — | CN | disclosed |
| US-20230250077-A1 | SULFONYLBENZAMIDE DERIVATIVE AND CONJUGATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD. (CN) | 2023-08-10 | — | — | US | disclosed |
| WO-2023142485-A1 | BORON-NITROGEN COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 季华恒烨(佛山)电子材料有限公司 | 2023-08-03 | — | — | WO | disclosed |
| CN-112552279-B | Synthesis method of substituted dibenzothiophene compound | 郑州海阔光电材料有限公司 | 2023-02-24 | — | — | CN | disclosed |
| CN-112480160-B | Second-order silane derivative, chiral third-order silane derivative, preparation method of chiral fourth-order silane derivative and chiral product of chiral fourth-order silane derivative | 清华大学 | 2022-02-11 | — | — | CN | disclosed |
| WO-2005084081-A1 | ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2005-09-09 | — | — | WO | disclosed |
| EP-0879814-B1 | Triaromatic compounds, compositions containing them and uses thereof | CT INTERNAT DE BR RECH S DERMA (FR) | 2001-11-28 | — | — | EP | disclosed |
| US-6150413-A | TREATMENT OF DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR, BONE AND OPHTHALMOLOGICAL DISORDERS, AS WELL AS MAMMALIAN SKIN AND HAIR CONDITIONS; 4-(4-(BIPHENYL-2-YL)BUT-3-EN-1-YNYL)BENZOIC ACID, FOR EXAMPLE | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2000-11-21 | — | — | US | disclosed |
| EP-0879814-A1 | Triaromatic compounds, compositions containing them and uses thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1998-11-25 | — | — | EP | disclosed |
| EP-0649424-B1 | DIOXCYCLOBUTENE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | KNOLL AG (DE) | 1998-10-07 | — | — | EP | disclosed |
| US-5627191-A | Therapeutic agents | THE BOOTS COMPANY PLC (GB) | 1997-05-06 | — | — | US | disclosed |
| EP-0649424-A1 | DIOXCYCLOBUTENE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | Knoll AG (DE) | 1995-04-26 | — | — | EP | disclosed |
| WO-1994001436-A1 | DIOXCYCLOBUTENE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | THE BOOTS COMPANY PLC (GB) | 1994-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250077-A1 | SULFONYLBENZAMIDE DERIVATIVE AND CONJUGATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | GLP1R, HADHB, SUCNR1 | ALDH1A1 226/4885MAPK1 2359/4885NPC1 2116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.