Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | LIPE | Q05469 | 3/20 | 0.36 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656790 | 0.86 | FFAR4 (0.43) | FFAR4LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL9653496 | 0.86 | KDM4E (0.45) | FFAR4LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL30990017 | 0.86 | KDM4E (0.45) | FFAR4LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL12611466 | 0.84 | NNMT (0.46) | FFAR4LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL10473574 | 0.84 | OPRK1 (0.46) | FFAR4LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL10474473 | 0.82 | TDP1 (0.43) | FFAR4LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL30989984 | 0.81 | PTGER4 (0.42) | SMN1; SMN2NPC1RAB9ASCN5ASCN9A | |
| SCHEMBL25449962 | 0.80 | ALDH1A1 (0.46) | FFAR4LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL25226894 | 0.80 | SLC13A5 (0.43) | LMNATSHRSMN1; SMN2MAPK1NPC1 | |
| SCHEMBL25228040 | 0.79 | GPBAR1 (0.43) | FFAR4LMNACYP2C9TSHRAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023111181-A1 | SMALL MOLECULE MODULATORS OF IL-17 | LEO PHARMA A/S (DK) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023111181-A1 | SMALL MOLECULE MODULATORS OF IL-17 | LEO PHARMA A/S (DK) | 2023-06-22 | — | — | WO | disclosed |
| US-4980357-A | ANTIDIABETIC AGENTS | PFIZER INC. (US) | 1990-12-25 | — | — | US | disclosed |
| WO-1989001775-A1 | AZOLIDINEDIONE DERIVATIVES | PFIZER INC. (US) | 1989-03-09 | — | — | WO | disclosed |
| EP-0306251-A2 | Azolidinedione derivatives | PFIZER INC. (US) | 1989-03-08 | — | — | EP | disclosed |