Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11335820 | 0.84 | KMT2A (0.70) | LMNAKMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8937769 | 0.82 | LMNA (0.47) | LMNAKMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11118026 | 0.79 | KMT2A (0.44) | LMNAKMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11689701 | 0.76 | KMT2A (0.53) | LMNAKMT2ARAB9AALDH1A1CYP1A2 | |
| SCHEMBL9703552 | 0.75 | — | — | |
| SCHEMBL9479526 | 0.75 | — | — | |
| SCHEMBL11687235 | 0.73 | HTT (0.52) | LMNAKMT2AALDH1A1CYP1A2 | |
| SCHEMBL9441451 | 0.72 | — | — | |
| SCHEMBL3244004 | 0.72 | — | — | |
| SCHEMBL3742866 | 0.72 | LMNA (0.48) | LMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267176-A | Amino or acylamino-substituted pyrimidinyl cephalosporanic acid derivatives and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-05-12 | — | — | US | claimed |
| US-4973699-A | Cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-11-27 | — | — | US | disclosed |
| US-4861769-A | Cephem compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-08-29 | — | — | US | disclosed |
| US-4338436-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| US-4338439-A | BACTERICIDAL ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| US-4319028-A | 7-(2-(Substituted benzoyl)amino)acetamido)cephalosporins | ELI LILLY AND COMPANY (US) | 1982-03-09 | — | — | US | disclosed |