Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11335820 | 0.79 | KMT2A (0.70) | KMT2ALMNAALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL10475166 | 0.79 | LMNA (0.48) | KMT2ALMNAALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8937769 | 0.78 | LMNA (0.47) | KMT2ALMNAALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL1223690 | 0.71 | — | — | |
| SCHEMBL3244004 | 0.69 | — | — | |
| SCHEMBL9441451 | 0.69 | — | — | |
| SCHEMBL8445215 | 0.67 | — | — | |
| SCHEMBL3245709 | 0.67 | — | — | |
| SCHEMBL9367428 | 0.67 | RAB9A (0.46) | KMT2ALMNARAB9ASMN1; SMN2 | |
| SCHEMBL22245499 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127847-A1 | 7-Oxo-4-thia-1-azabicyclo(3.2.0)hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1984-12-12 | — | — | EP | disclosed |