Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.56 |
| ▸ | MAPK8 | P45983 | 15/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.56 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.56 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.56 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.56 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10474593 | 0.89 | KCNH2 (0.56) | P2RX3MAPK8PIM1IRAK1CAMK2B | |
| SCHEMBL7128069 | 0.86 | PIM1 (0.56) | P2RX3PIM1IRAK1CAMK2BCAMK2G | |
| SCHEMBL5101006 | 0.86 | NR4A2 (0.59) | P2RX3PIM1IRAK1CAMK2BCAMK2G | |
| SCHEMBL31513796 | 0.84 | NPC1 (0.60) | P2RX3PIM1IRAK1CAMK2BCAMK2G | |
| SCHEMBL27968930 | 0.83 | P2RX3 (0.75) | P2RX3ALDH1A1LMNAMAPT | |
| SCHEMBL10475559 | 0.83 | MAPK8 (0.58) | MAPK8 | |
| SCHEMBL10472497 | 0.83 | KMT2A (0.59) | PIM1IRAK1CAMK2BCAMK2GCAMK2D | |
| SCHEMBL30417213 | 0.83 | KMT2A (0.59) | PIM1IRAK1CAMK2BCAMK2GCAMK2D | |
| SCHEMBL6050613 | 0.82 | BAZ2B (0.54) | P2RX3PIM1IRAK1CAMK2BCAMK2G | |
| SCHEMBL30906936 | 0.81 | LMNA (0.63) | P2RX3ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959363-A | HERPES VIRUS | STERLING DRUG INC. (US) | 1990-09-25 | — | — | US | disclosed |