Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RHEB | Q15382 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10362234 | 0.82 | HTR2A (0.58) | SLC6A2SLC6A4SLC6A3KCNH2HTR2A | |
| SCHEMBL10362247 | 0.77 | GAA (0.46) | SLC6A4MAPTKCNH2ALDH1A1HTR2A | |
| SCHEMBL10474818 | 0.75 | SLC6A4 (0.42) | SLC6A2SLC6A4SLC6A3MAPTHPGD | |
| SCHEMBL10362332 | 0.75 | MAPT (0.36) | SLC6A2SLC6A4SLC6A3MAPTNFE2L2 | |
| SCHEMBL12377073 | 0.75 | AR (0.42) | SLC6A4MAPTNFE2L2HPGDKDM4E | |
| SCHEMBL8986207 | 0.74 | KDM4E (0.50) | SLC6A4MAPTNFE2L2HPGDKDM4E | |
| SCHEMBL10363891 | 0.73 | CACNA1B (0.45) | SLC6A2SLC6A4SLC6A3NFE2L2HPGD | |
| SCHEMBL10781099 | 0.71 | NFE2L2 (0.41) | NFE2L2KDM4EALDH1A1TSHR | |
| SCHEMBL5323516 | 0.70 | LMNA (0.60) | SLC6A2SLC6A4SLC6A3PLA2G1BMAPT | |
| SCHEMBL1436765 | 0.70 | HPGD (0.59) | SLC6A2SLC6A4SLC6A3CXCL8HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990003965-A1 | ARYLOXY-, ARYLTHIO-, HETEROARYLOXY-, HETEROARYLTHIO-ALKENYLENE DERIVATIVES OF AMINES | FARMITALIA CARLO ERBA S.R.L. (IT) | 1990-04-19 | — | — | WO | disclosed |